Audriana Nicole Hurbon

Interests

No activities entered.

Courses

No activities entered.

Scholarly Contributions

Journals/Publications

• Gondal, A., Hsu, C., Serrot, F., Rodriguez-Restrepo, A., Hurbon, A., Galvani, C., & Ghaderi, I. (2019). Enhanced Recovery in Bariatric Surgery: A Study of Short-Term Outcomes and Compliance. Obesity Surgery, 29(2). doi:10.1007/s11695-018-3579-z
  More info

  Introduction: The implementation of Enhanced Recovery After Surgery (ERAS) guidelines has been widely studied among various surgical specialties. We aimed at comparing the perioperative outcomes and compliance with ERAS protocol in bariatric surgery at our center. Methods: An observational review of a prospectively maintained database was performed. Patients who underwent primary bariatric surgery (gastric bypass or sleeve gastrectomy) between January 2011 and June 2018 were included. Patients were divided into pre- and post-ERAS groups. Data including basic demographic information, length of hospital stay, 30-day perioperative complications, and readmission rates were collected. Compliance with elements of ERAS was assessed using a combination of chart review and a prospectively implemented checklist. P < 0.05 was chosen to be statistically significant. Results: A total of 435 patients were included: 239 patients in the pre-ERAS group and 196 patients in the post-ERAS group. There were no statistical differences in baseline demographics and major comorbidities between the 2 groups. The post-ERAS group had shorter length of hospital stay (2.23 vs 1.23, p < 0.001) and lower rates of 30-day postoperative morbidity (8.7 vs 4%, p =.04). There was no significant difference between the 2 groups with respect to readmissions rates. There was no mortality in either group. Overall compliance rates with ERAS elements were 85%; compliance increased significantly with the implementation of a checklist (p < 0.001). Conclusions: Implementation of ERAS program for bariatric surgery is safe and feasible. It reduces hospital stay and postoperative morbidity. Easy to implement strategies such as checklists should be encouraged in bariatric programs to aid in implementation and compliance with ERAS elements for perioperative care.
• Gondal, A. B., Hsu, C., Serrot, F. J., Rodríguez-Restrepo, A., Hurbon, A. N., Galvani, C., & Ghaderi, I. (2018). Enhanced Recovery in Bariatric Surgery: A Study of Short-Term Outcomes and Compliance. Obesity Surgery. doi:10.1007/s11695-018-3579-z
• Adamas‐Rappaport, W. J., Cervantes, J. A., Faucett, E. A., Hurbon, A. N., Kent, S. L., McCrary, H. C., & Milinic, T. (2017). A Fresh Cadaver Model for the Instruction of Ultrasound‐Guided Fine‐Needle Aspiration of Thyroid Nodules. Otolaryngology–Head and Neck Surgery, 157(1), 30-35. doi:10.1177/0194599817699596
  More info

  Objective The aim of our study is to determine if a fresh cadaver model (FCM) for the instruction of ultrasound (US)-guided fine-needle aspiration (FNA) of thyroid nodules is a practical method for instruction. Study Design Pre- and postinstruction assessment of medical students' ability to perform US-guided FNA of artificially created thyroid nodules placed adjacent to the thyroid gland of a fresh cadaver. Setting University-based fresh cadaver laboratory. Subjects and Methods Study participants included a total of 17 first- and second-year medical students with minimal US training. Technical skills were assessed using a 10-item checklist. In addition, a cognitive assessment regarding the indications, contraindications, and complications of the procedure was completed. A postinstruction assessment was provided for participants 5 weeks after their initial assessment. Differences between pre- and postinstruction assessment scores of technical skills were analyzed using McNemar's test. The mean cognitive knowledge gain was analyzed using a paired 2-sample t test. Results Eight of 10 items on the skills checklist were statistically significant between pre- and postinstruction skills assessment ( P < .05). There was a statistically significant change in cognitive knowledge gain regarding the contraindications of the procedure ( P = .001), but not for indications or complications ( P = .104 and P = .111, respectively). Conclusion US-guided FNA continues to be an important diagnostic procedure in the workup of thyroid nodules, making it an essential skill to integrate into surgical skills lab. Our FCM for the instruction of US-guided FNA is the first of its kind, and this pilot study shows this is a viable method for instruction.
• McCrary, H., Faucett, E., Hurbon, A., Milinic, T., Cervantes, J., Kent, S., & Adamas-Rappaport, W. (2017). A Fresh Cadaver Model for the Instruction of Ultrasound-Guided Fine-Needle Aspiration of Thyroid Nodules. Otolaryngology - Head and Neck Surgery (United States), 157(1). doi:10.1177/0194599817699596
  More info

  Objective: The aim of our study is to determine if a fresh cadaver model (FCM) for the instruction of ultrasound (US)–guided fine-needle aspiration (FNA) of thyroid nodules is a practical method for instruction. Study Design: Pre- and postinstruction assessment of medical students’ ability to perform US-guided FNA of artificially created thyroid nodules placed adjacent to the thyroid gland of a fresh cadaver. Setting: University-based fresh cadaver laboratory. Subjects and Methods: Study participants included a total of 17 first- and second-year medical students with minimal US training. Technical skills were assessed using a 10-item checklist. In addition, a cognitive assessment regarding the indications, contraindications, and complications of the procedure was completed. A postinstruction assessment was provided for participants 5 weeks after their initial assessment. Differences between pre- and postinstruction assessment scores of technical skills were analyzed using McNemar’s test. The mean cognitive knowledge gain was analyzed using a paired 2-sample t test. Results: Eight of 10 items on the skills checklist were statistically significant between pre- and postinstruction skills assessment (P
• Platto, T., Hurbon, A. N., Igarashi, S., Meister, E. A., Dunn, A., & Jacob, A. (2014). A Novel High‐Throughput Ototoxicity Assay in Zebrafish: Platform for Drug Development Targeting Hearing Loss. Sage. doi:10.1177/0194599814541627a202
  More info

  Objectives: Develop a functional assay of zebrafish (Danio rerio) swimming behavior correlated with anatomic studies of hair cells along the lateral line as a platform for high‐throughput drug development against hearing loss. Methods: In vivo animal study at university animal care facilities. Five‐day postfertilization (dpf) zebrafish were treated with 0 (control)‐1000 µM concentrations of cisplatin. In darkness, swimming behavior was analyzed using infrared video systems housed within a novel, multilane, high throughput apparatus to calculate the rheotaxis index (RI). The RI, which represents the ability of fish to properly orient relative to water current, allowed direct comparison of various cisplatin doses to controls simultaneously. Hair cells of zebrafish exposed to cisplatin were also stained with Yo‐Pro1 and imaged using confocal microscopy in order to correlate anatomic changes with changes in swimming behavior. Results: A dose‐dependent relationship between cisplatin concentration and RI was found. 0 µM (control): RI 39.85%; 250 µM: RI 38.11%; 500 µM: RI 25.12%; 750 µM: RI 22.97%; 1000 µM: RI 17.84%. The decline in rheotaxis performance correlated directly with increasing dosage of cisplatin. Conclusions: There are currently no Food and Drug Administration–approved pharmacological treatments for hearing loss. Using a validated behavioral assay to test ototoxic dose of cisplatin against varying concentrations of potentially otoprotective/otoregenerative compounds establishes a first‐ever, high‐throughput biologic platform for drug development against hearing loss.

Presentations

• Hurbon, A. (2024, Spring). The Impact of Reproductive History on Pulmonary Hypertension: Insights from the PVDOMICs study. American Thoracic Society/ Oral Presentation. San Diego, California: None.