Bujji B Ainapurapu

Interests

Teaching

Bedside teaching- clinical examination, communication with patients.Small group teaching like morning reports.

Research

Quality improvement projects

Courses

No activities entered.

Scholarly Contributions

Journals/Publications

• Khludenev, G., Le Cam, E., & Ainapurapu, B. B. (2023). Non-diabetic Euglycemic Ketoacidosis in an Adult Patient With Spinal Muscular Atrophy Type II. Cureus, 15(9), e45666.
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  Spinal muscular atrophy (SMA) is a rare neuromuscular disease that develops as a result of the degeneration of the anterior horn cells in the spinal cord and lower brainstem motor nuclei, resulting in progressive muscle weakness and atrophy. While the initial presentation of this disease involves diffuse muscular atrophy at an early age, patients with an established diagnosis and later-stage disease often present with gastrointestinal symptoms related to metabolic imbalances. Here, we examine the case of an adult patient with SMA type II who presented with complaints of 12 hours of intractable nausea and vomiting. The patient was found to be in euglycemic ketoacidosis (EKA), an uncommon, but not unheard of, metabolic derangement in SMA patients with severely decreased muscle mass.
• Blackstone, N., Olson, A., & Ainapurapu, B. B. (2020). Physostigmine in Anticholinergic poisoning: An old antidote with resurgence. Cureus, 12(11). doi:10.7759/cureus.111739
• Siordia, J., Uhland, C., & Ainapurapu, B. B. (2020). Pomalidomide-Induced Lung Injury Mimicking COVID19 Pneumonia. Journal of Medical Case Reports, 3.
• Pahuja, M., Ainapurapu, B., & Abidov, A. (2017). Large Left Ventricular Thrombus in a Patient with Systemic and Venous Thromboembolism Secondary to Protein C and S Deficiency.. Case reports in cardiology, 2017, 7576801. doi:10.1155/2017/7576801
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  58-year-old Hispanic female presented with an altered mental status. A CT scan of the head demonstrated multiple scattered infarcts and a large right temporal lobe infarct. We also diagnosed the patient with right popliteal and femoral vein thrombosis, bilateral pulmonary embolism, and a transient right radial artery occlusion. Her 12-lead EKG showed lateral ST elevation. Emergent coronary angiogram revealed normal coronaries. Echocardiogram demonstrated a large mobile mass attached to the anterolateral free wall with overall normal contractility of the left ventricle. The patient underwent surgical embolectomy to prevent further systemic embolization. Coagulability workup returned positive for protein C and S deficiency. The patient did well after surgery. Following her surgery, we initiated chronic oral anticoagulation. The presentation with intracardiac thrombus in a normal heart should raise a concern of a probable thrombophilia.
• Ainapurapu, B. (2015). Familiarity Breeds Contempt: "Frequent Fliers" in Medicine. Southern medical journal, 108(12), 701.
• Hagio, T., Huang, C., Abidov, A., Singh, J., Ainapurapu, B., Squire, S., Bruck, D., & Altbach, M. I. (2015). T2 mapping of the heart with a double-inversion radial fast spin-echo method with indirect echo compensation. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 17, 24.
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  The abnormal signal intensity in cardiac T2-weighted images is associated with various pathologies including myocardial edema. However, the assessment of pathologies based on signal intensity is affected by the acquisition parameters and the sensitivities of the receiver coils. T2 mapping has been proposed to overcome limitations of T2-weighted imaging, but most methods are limited in spatial and/or temporal resolution. Here we present and evaluate a double inversion recovery radial fast spin-echo (DIR-RADFSE) technique that yields data with high spatiotemporal resolution for cardiac T2 mapping.
• Kanakadandi, U. B., & Ainapurapu, B. (2014). Trimethoprim-sulfamethoxazole induced rhabdomyolysis.. American journal of therapeutics, 21(3), e78-9. doi:10.1097/mjt.0b013e31824567fe
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  Empiric antibiotic usage is very common in clinical practice and Trimethoprim-Sulfamethoxazole (TMP-SMX) is one such antibiotic used extensively in primary care practice. Some patients experience serious adverse effects to the antibiotics that markedly increase the morbidity and the cost of medical care. We describe one such patient, a previously healthy 40-year-old Hispanic female who developed myositis and rhabdomyolysis secondary to TMP-SMX. To the best of our knowledge, this is the first report of TMP-SMX-induced rhabdomyolysis in an immunocompetent host.
• Ainapurapu, B., Galons, J. P., Squire, S., Singh, J., Kc, D. B., Huang, C., Galons, J. P., Barr, T., Altbach, M. I., Ainapurapu, B., & Abidov, A. (2012). T2 mapping of the heart with high temporal and spatial resolution using a radial double inversion fast spin-echo pulse sequence with view sharing. Journal of Cardiovascular Magnetic Resonance, 14(1), 1-2. doi:10.1186/1532-429x-14-s1-o112
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  Summary A double inversion radial fast spin echo (DIR-RADFSE) has been developed to obtain T2 maps of the heart with high-temporal and spatial resolution from data acquired in as ingle breath hold. The method allows for the quantitative assessment of inflammation in the heart. Background While DE imaging is considered a gold standard in the evaluation of myocardial scar/viability in patients with old MI or cardiomyopathy, a few recent publications demonstrate a higher diagnostic sensitivity of T2weighted techniques in patients with Non-STEMI and myocarditis where changes in T2-weighting are due to inflammation in the myocardium leading to edema (Abdel-Aty H, JACC 53:1194, 2009; Tilak GS, Invest
• Kenkare, S., & Ainapurapu, B. (2010). Macrodactylia fibrolipomatosis presenting as a small bowel obstruction.. Southern medical journal, 103(3), 248-9. doi:10.1097/smj.0b013e3181ce0e36
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  A patient presented with progressive abdominal distention, discomfort, nausea, vomiting, and constipation. The patient also had congenital macrodactyly of the third, fourth, and fifth digits of the left hand. He [corrected] was diagnosed with macrodactylia fibrolipomatosis with multiple small bowel lipomas and complete small bowel obstruction. Macrodactylia fibrolipomatosis is a rare condition characterized by benign fibrofatty infiltration involving the soft tissues of the distal arm or leg with associated dactylomegaly of the associated digits. This patient had a rare presentation that included extensive small bowel lipomatosis.

Proceedings Publications

• Ainapurapu, B., Uhland, C., & Siordia, J. (2021). Pomalidomide-Induced Lung Injury Mimicking COVID19 Pneumonia. In American Thoracic Society.

Presentations

• Ainapurapu, B. B., Ainapurapu, B. B., Shirazi, F., Shirazi, F., Swazo, R., Swazo, R., Ainapurapu, B. B., Shirazi, F., & Swazo, R. (2019, May). Confused and Belligerent Professor. Medicine Grand Rounds/CPC. UACOM.

Poster Presentations

• Ainapurapu, B. B., Long, M., & Pham, H. Y. (2023, October). More than meets the eye: A case of acute onset diffuse systemic sclerosis. ACP AZ Chapter Meeting. Tempe, AZ: ACP.
• Kumar, S., Power, E., & Ainapurapu, B. B. (2018, Oct). How to aDRESS complication of Allopurinol. ACP-AZ chapter. Tempe: ACP.
• Ainapurapu, B. B., & Blumenkron, F. (2017, October). • Uncommitted to this Ring. ACP-AZ chapter meetingAmerican College of Physicians.
• Ainapurapu, B. B., & Britt, J. (2017, October). Too many platelets and still bleeding!. ACP-AZ Chapter MeetingACP.
• Ainapurapu, B. B., & Kannaiyan, R. (2017, October). The story of a Catwoman. ACP-AZ chapter meetingACP.
• Ainapurapu, B. B., O'Hara, G., & Danawala, L. (2017, October). Anaplastic Large Cell Lymphoma with Cutaneous Involvement. ACP-AZ chapter meetingACP.
• Ainapurapu, B. B., Swazo, R., & Lam, P. (2017, October). From birth control to blindness. ACP-AZ Chapter Meeting.
• Ainapurapu, B. B., Yousman, W., & Huang, J. (2017, October). Rapidly Progressive Cardiac Allograft Vasculopathy in a Heart Transplant Patient. ACP-AZ Chapter MeetingACP.
• Khare, S. B., Jasper, S., & Khare, S. (2017, October). Cushing’s syndrome and The Lost Art of History and Physical Examination. ACP-AZ chapter meetingACP.
• Tariq, S., Ainapurapu, B. B., & Jaswal, N. (2017, October). The disappearing mole act. ACP-AZ Chapter Meeting.
• August, J., Ainapurapu, B. B., & Zangeneh, T. T. (2016, May). Running Out of Sight- Neuroretinitis secondary to Borrelia Hermsii infection. ACP NationalsAmerican College of Physicians National Meeting.
• Ainapurapu, B. B. (2015, 10/Fal). An unusual cause of a common complaint. ACP-AZ Chapter meeting. Tucson: ACP.
• Jaffer, F., Patel, S., Potharaju, A., Bruzzi, B., & Ainapurapu, B. B. (2015, 10/Fall). Impact of Resident Education in System based practice to improve patient care. ACP-AZ chapter meeting. Tucson: ACP.
• Sandoval, J., Salazar, B., & Ainapurapu, B. B. (2015, 10/Fall). Cranial Germinoma: A rare cause of Panhypopituarism. ACP-AZ chapter meeting. Tucson: ACP.
• Singh, N., Natt, B., Ainapurapu, B. B., & Trowers, E. A. (2015, November/Fall). Hereditary Spherocytosis Leading to Pulmonary Hypertension. American College of Physicians Arizona Meet. Tucson, AZ.

Reviews

• Blohm, J. E., Panthula, M., Aggarwal, A., Swazo, R., Ashoka, A., & Ainapurapu, B. (2023. Fatal Disseminated Coccidioidomycosis in Cirrhosis: A Case Series(pp 707-709).
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  Coccidioidomycosis is endemic to the Southwest United States and Mexico. In this case series we describe 3 cases, occurring in the Southwest United States, of patients with disseminated coccidioidomycosis infection in cirrhosis, all with a miliary pattern present on chest imaging.

Others

• Ainapurapu, B. B., Acuna, J., Adhikari, S. R., Situ-LaCasse, E., & Siordia, J. (2020, October). Does Artificial Intelligence guidance help Internal Medicine residents acquire better diagnostic point of care ultrasound images. Research Project.
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  This is a research project where we tested whether artificial intelligence (AI) guidance using caption health device helps IM residents to get better diagnostic quality images. This was done on standardized patients and surveys were also conducted on whether performers felt the AI guidance was helpful or not. Project is currently underway.