David S Chen

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Scholarly Contributions

Chapters

• Gossett, K., Chen, D., & Loyo, M. (2021). Innervation options for gracilis free muscle transfer in facial reanimation.. In Plast Aesthet Res. 8(60).
• Chen, D., & Wang, T. (2020). Management of Dorsal Graft and Implant Infections.. In Facial Plast Surg.(pp 24-27). 36(1).
• Chen, D., Boahene, K., Eisele, D., & Fakhry, C. (2020). Buccal Reconstruction.. In Oral Cancer: Evaluation, Therapy, and Rehabilitation.(pp 154-159). New York: Thieme.

Journals/Publications

• Johnson, A. J., & Chen, D. S. (2023). Office-based facial plastics procedures: Neuromodulators. World journal of otorhinolaryngology - head and neck surgery, 9(3), 220-226.
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  Botulinum toxin is a potent neuromodulator commonly used for cosmetic applications in the clinic. In this article, we reviewed the various formulations of botulinum toxin type A commercially available in the United States, as well as clinical pearls for preprocedural planning, common in-office injections, and management of complications.
• Kumar, A. R., Ishii, L. E., Papel, I., Kontis, T. C., Chen, D., Liao, D., Chen, J., Nellis, J., & Ishii, M. (2020). The Valuation of Rhytidectomy in Different Economic Markets. Facial plastic surgery : FPS, 36(5), 665-669.
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  This study demonstrates that the trend of how rhytidectomy is valued can be used to determine not only the pricing of this good but also how receptive developing economic markets are to the export of cosmetic facial plastic surgery. This study seeks to analyze and compare the value of rhytidectomy in an established market and an emerging market. A cross-sectional survey was administered through public online forums to 162 casual observers in the United States and 74 casual observers in India. Participants were shown pre- and postoperative photos of 10 patients who underwent cosmetic rhinoplasty and 2 patients who did not undergo surgery. Observers were asked to quantify the perceived change in attractiveness, change in age, and willingness to pay (WTP). There is a similar nonlinear trend between WTP and change in attractiveness in both the United States and India. Baseline values of rhytidectomy in the United States and India have a similar ratio of 2.122 compared with the ratio between both countries in the 2018 Big Mac index. The comparison of the trend in WTP in the United States and India shows that facial cosmetic surgery functions as a luxury good in both an established market and an emerging market. Our model successfully approximates the relationship between each country's purchasing power parity. Since the market behavior of rhytidectomy can be predicted based on purchasing power parity, there may be an untapped market for facial cosmetic surgery among populations with growing economies.
• Oliver, J. R., Chen, D. S., Pearl, M. S., Carey, J. P., & Sun, D. Q. (2020). Carotid Artery-Cochlear Dehiscence. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 41(2), e290-e292.
• Chen, D., Ishii, M., Nellis, J., Bater, K., Darrach, H., Liao, D., Joseph, A., Byrne, P., Boahene, K., Papel, I., Kontis, T., & Ishii, L. E. (2019). Assessment of Casual Observers' Willingness to Pay for Increased Attractiveness Through Rhinoplasty. JAMA facial plastic surgery, 21(1), 27-31.
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  Contingent valuation, or willingness to pay, is an established economic concept that has been applied in other areas of medicine and may be useful for understanding the economic forces that determine the cost of cosmetic procedures.
• Chen, D., Britt, C. J., Mydlarz, W., & Desai, S. C. (2018). A novel technique for tracheal reconstruction using a resorbable synthetic mesh. The Laryngoscope, 128(7), 1567-1570.
• Li, L., Blake, C., Sung, Y., Shpritz, B., Chen, D., Genther, D. J., Betz, J., & Lin, F. R. (2017). The Studying Multiple Outcomes After Aural Rehabilitative Treatment Study: Study Design and Baseline Results. Gerontology & geriatric medicine, 3, 2333721417704947.
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  Hearing loss may affect critical domains of health and functioning in older adults. This article describes the rationale and design of the Studying Multiple Outcomes After Aural Rehabilitative Treatment (SMART) study, which was developed to determine to what extent current hearing rehabilitative therapies could mitigate the effects of hearing loss on health outcomes. One hundred and forty-five patients ≥50 years receiving hearing aids (HA) or cochlear implants (CI) were recruited from the Johns Hopkins Department of Otolaryngology-HNS. A standardized outcome battery was administered to assess cognitive, social, mental, and physical functioning. Of the 145 participants aged 50 to 94.9 years who completed baseline evaluations, CI participants had significantly greater loneliness, social isolation, and poorer hearing and communicative function compared with HA participants. This study showed that standardized measures of health-related outcomes commonly used in gerontology appear sensitive to hearing impairment and are feasible to implement in clinical studies of hearing loss.
• Choi, J. S., Betz, J., Deal, J., Contrera, K. J., Genther, D. J., Chen, D. S., Gispen, F. E., & Lin, F. R. (2016). A Comparison of Self-Report and Audiometric Measures of Hearing and Their Associations With Functional Outcomes in Older Adults. Journal of aging and health, 28(5), 890-910.
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  The aim was to investigate whether associations of hearing impairment (HI) with functional outcomes in older adults differ when using self-report versus pure-tone audiometry.
• Chen, D. S., Betz, J., Yaffe, K., Ayonayon, H. N., Kritchevsky, S., Martin, K. R., Harris, T. B., Purchase-Helzner, E., Satterfield, S., Xue, Q. L., Pratt, S., Simonsick, E. M., Lin, F. R., & , H. A. (2015). Association of hearing impairment with declines in physical functioning and the risk of disability in older adults. The journals of gerontology. Series A, Biological sciences and medical sciences, 70(5), 654-61.
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  Identifying factors associated with functional declines in older adults is important given the aging of the population. We investigated if hearing impairment is independently associated with objectively measured declines in physical functioning in a community-based sample of older adults.
• Genther, D. J., Laudenslager, M. L., Sung, Y. K., Blake, C. R., Chen, D. S., & Lin, F. R. (2015). Assessing Systemic Stress in Otolaryngology: Methodology and Feasibility of Hair and Salivary Cortisol Testing. Journal of nature and science, 1(8).
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  Elevated systemic stress is a predictor of adverse health outcomes, and stress can be objectively quantified by cortisol concentration. Despite its utility, such testing is rarely performed in otolaryngology. This manuscript provides details on the principles, methodology, and feasibility of performing laboratory assessments of hair and salivary cortisol to inform researchers wishing to incorporate these novel tests in future otolaryngologic studies.
• Chen, D. S., Blake, C. R., Genther, D. J., Li, L., & Lin, F. R. (2014). Assessing physical functioning in otolaryngology: feasibility of the Short Physical Performance Battery. American journal of otolaryngology, 35(6), 708-12.
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  Objective measures of physical functioning and mobility are considered to be the strongest indicators of overall health and mortality risk in older adults. These measures are not routinely used in otolaryngology research. We investigated the feasibility of using a validated physical performance battery to assess the functioning of older adults seen in a tertiary care otolaryngology clinic.
• Chen, D. S., Genther, D. J., Betz, J., & Lin, F. R. (2014). Association between hearing impairment and self-reported difficulty in physical functioning. Journal of the American Geriatrics Society, 62(5), 850-6.
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  To determine whether hearing impairment, defined by using objective audiometry, is associated with multiple categories of self-reported physical functioning in a cross-sectional, nationally representative sample of older adults.
• Chen, D. S., Clarrett, D. M., Li, L., Bowditch, S. P., Niparko, J. K., & Lin, F. R. (2013). Cochlear implantation in older adults: long-term analysis of complications and device survival in a consecutive series. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 34(7), 1272-7.
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  To analyze the postoperative complications associated with cochlear implant (CI) surgery in a large consecutive case series of older adults (≥ 60 yr).
• Genther, D. J., Frick, K. D., Chen, D., Betz, J., & Lin, F. R. (2013). Association of hearing loss with hospitalization and burden of disease in older adults. JAMA, 309(22), 2322-4.
• Mener, D. J., Betz, J., Genther, D. J., Chen, D., & Lin, F. R. (2013). Hearing loss and depression in older adults. Journal of the American Geriatrics Society, 61(9), 1627-9.
• Baskaran, M., Ong, E. L., Li, J. L., Cheung, C. Y., Chen, D., Perera, S. A., Ho, C. L., Zheng, Y. F., & Aung, T. (2012). Classification algorithms enhance the discrimination of glaucoma from normal eyes using high-definition optical coherence tomography. Investigative ophthalmology & visual science, 53(4), 2314-20.
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  To evaluate the diagnostic performance of classification algorithms based on Linear Discriminant Analysis (LDA) and Classification And Regression Tree (CART) methods, compared with optic nerve head (ONH) and retinal nerve fiber layer (RNFL) parameters measured by high-definition optical coherence tomography (Cirrus HD-OCT) for discriminating glaucoma subjects.
• Cheung, C. Y., Chen, D., Wong, T. Y., Tham, Y. C., Wu, R., Zheng, Y., Cheng, C. Y., Saw, S. M., Baskaran, M., Leung, C. K., & Aung, T. (2011). Determinants of quantitative optic nerve measurements using spectral domain optical coherence tomography in a population-based sample of non-glaucomatous subjects. Investigative ophthalmology & visual science, 52(13), 9629-35.
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  To evaluate the ocular and systemic factors influencing measurements of optic nerve head (ONH) parameters and retinal nerve fiber layer (RNFL) thickness with spectral-domain optical coherence tomography (SD-OCT) in healthy Chinese adults.
• Miyashita, T., Armstrong, T., Wang, J., Gibson, M., Chen, D., Yoshimura, K., Mohebi, P., Marti, G., Montgomery, E., Duncan, M., & Harmon, J. (2007). Granulocyte macrophage colony stimulating factor (GM-CSF) transfected vaccine for esophageal cancer causes regression of subcutaneous implants in rats.. Journal of Surgical Research, 137(2), 194-195.

Presentations

• Chen, D. (2023, August). Local Flaps. U of A Department of Dermatology Grand Rounds. Tucson, AZ.
• Chen, D. (2023, February). Treatment of Facial Paralysis. ENT in the Desert. Tucson, AZ: University of Arizona.
• Chen, D. (2022, February). Panel Speaker-- Evaluation of the Patient with Nasal Obstruction. ENT in the Desert. Tucson, AZ: University of Arizona.
• Chen, D. (2022, February). To Rib or Not to Rib? -- AUtologous and Cadaveric Costal Cartilage Grafts in Rhinoplasty. ENT in the Desert. Tucson, AZ: University of Arizona.
• Chen, D. (2022, January). Panel: Surgical Decision Making and Objective Technique in Rhinoplasy.. Rush Update in Otolaryngology. Chicago, IL.
• Chen, D. (2022, Marcy). An Overview of Facial Reanimation. U of A Deparment of Ophthalmology Grand Rounds. Tucson, AZ.
• Chen, D. (2021, December). Nasal Reconstruction. U of A Deparment of Dermatology Grand Rounds. Tucson, AZ.
• Chen, D. (2021, November). An Overview of Facial Reanimation. U of A Department of Otolaryngology Grand Rounds. Tucson, AZ.
• Chen, D., Ishii, M., Nellis, J., Bater, K., Darrach, H., Liao, D., Joseph, A., Byrne, P., Boahene, K., Papel, I., Kontis, T., & Ishii, L. (2017). Willingness to Pay for Increased Attractiveness through Rhinoplasty.. Combined Otolaryngological Spring Meetings.
• Chen, D., Betz, J., Yaffe, K., Ayonayon, H., Kritchevsky, S., Martin, K., Harris, T., Purchase-Helzner, E., Satterfield, S., Xue, Q., Pratt, S., Simonsick, E., & Lin, F. (2013). Association of Hearing Impairment with Physical Functioning Decline in Older Adults.. Gerontological Society of America Annual Meeting.
• Chen, D., Betz, J., Yaffe, K., Ayonayon, H., Kritchevsky, S., Martin, K., Harris, T., Purchase-Helzner, E., Satterfield, S., Xue, Q., Pratt, S., Simonsick, E., & Lin, F. (2013). Association of Hearing Loss with Physical Functioning Decline in Older Adults. Combined Otolaryngological Spring Meetings.
• Chen, D., Clarrett, D., Li, L., Bowditch, S., Niparko, J., & Lin, F. (2013). Complications Following Cochlear Implantation in Older Adults.. Combined Otolaryngological Spring Meetings.

Poster Presentations

• Chen, D., Bynum, J., Schmitt, N., & Mydlarz, W. (2016). Rosai-Dorfman Disease of the Head and Neck – Diagnosis and Management in an Elderly Patient.. Triological Society Annual Meeting, Combined Otolaryngology Spring Meetings.
• Chen, D., Betz, J., Yaffe, K., Ayonayon, H., Kritchevsky, S., Martin, K., Harris, T., Purchase-Helzner, E., Purchase-Helzner, S., Xue, Q., Pratt, S., Simonsick, E., & Lin, F. (2013). Association of Hearing Loss with Physical Functioning Decline in Older Adults.. Aging Symposium, Johns Hopkins Bloomberg School of Public Health.
• Chen, D., Clarrett, D., Li, L., Bowditch, S., Niparko, J., & Lin, F. (2013). Complications Following Cochlear Implantation in Older Adults. Aging Symposium, Johns Hopkins Bloomberg School of Public Health, Baltimore.
• Chen, D., Cheung, C., Wong, T., & Tham, Y. (2011). Determinants of Quantitative Optic Nerve Measurements using Spectral Domain Optical Coherence Tomography in a Population-based Sample of Non-glaucomatous Subjects.. Association for Research in Vision and Ophthalmology Annual Meeting.