Eliot M Herman

Interests

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Courses

Scholarly Contributions

Chapters

• Ferrieri, R., Herman, E. M., Babst, B., & Schueller, M. (2019). Managing the soil nitrogen cycle in agrosystems.. In In Soil Nitrogen Uses and Environmental Impacts, Ed. Rattan Lal, BA Stewart, Chapter 14,. CRC Press.
• Herman, E. M. (2017). Reducing allergenic properties in soybean. Achieving sustainable cultivation of soybeans. In Achieving sustainable cultivation of soybeans. Burleigh Dodds Science Publishing Limited.
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  Invited chapter in a book on soybeans edited by Henry Nguyen.
• Herman, E. M., & Chrispeels, M. (2017). Traits that benefit farmers and industry.. In Plants, Genes and Agriculture: Sustainability through biotechnology(pp n/a). Sinauer Associates, Sutherland, MA.
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  Chapter in textbook for general education course.
• Herman, E. M., & Chrispeels, M. (2017). Traits that benefit the food industry and the consumer.. In Plants, Genes and Agriculture. Sinauer Associates, Sutherland, MA.
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  Chapter in textbook for undergraduate general education course.
• Ferrieri, R., Herman, E. M., Babst, B., & Schueller, M. (2018). Managing the soil nitrogen cycle in agrosystems.. In In Soil Nitrogen Uses and Environmental Impacts, Ed. Rattan Lal, BA Stewart, Chapter 14,. CRC Taylor Francis.
• Herman, E. M. (2018). Reducing allergenic properties in soybean. Achieving sustainable cultivation of soybeans. In Achieving sustainable cultivation of soybeans(pp 235-256). Cambridge UK: Burleigh Dodds Science Publishing Limited.
  More info

  Invited chapter in a book on soybeans edited by Henry Nguyen.
• Chrispeels, M., & Herman, E. M. (2017). Traits that benefit the food industry and the consumer.. In Plants, Genes and Agriculture. Sinauer Associates, Sutherland, MA.
  More info

  Chapter in textbook for undergraduate general education course.

Journals/Publications

• Krogdahl, A., Kortner, T., Gamil, A., Chikwati, E., Schmidt, M., Herman, E. M., Hymowitz, T., Teimouri, S., Kandel, S., & Storebakken, T. (2019). Soybean meal without Kunitz trypsin inhibitor, lectin and allergen P34/Gly m Bd 30k as protein source in diets for Atlantic salmon (Salmo salar, L) induce enteritis. Aquaculture.
• Krogdahl, A., Kortner, T., Gamil, A., Chikwati, E., Schmidt, M., Herman, E. M., Hymowitz, T., Teimouri, S., Kandel, S., & Storebakken, T. (2020). Soybean meal without Kunitz trypsin inhibitor, lectin and allergen P34/Gly m Bd 30k as protein source in diets for Atlantic salmon (Salmo salar, L) induce enteritis. Aquaculture.
• Hashimoto-Hill, S., Kim, M., Freisen, L., Kolap, A., Herman, E. M., Schinkel, A., & Kim, C. (2019). Differential food allergy responses in outbred swine lines selected for reactivity to soy antigens. Allergy.
• Schinckel, A., Herman, E. M., Schmidt, M., Reddivari, L., Brito, L., & Radcliffe, J. (2019). A swine model of soy protein-induced food allergenicity: implications in human and swine nutrition. Animal Frontiers, 9(3), 52-59.
• Herman, E. M., & Schmidt, M. A. (2018). Characterization and functional biology of the soybean aleurone layer. BMC Plant Biology.
• Herman, E. M., & Schmidt, M. (2016). The potential of engineering functional-feed soybeans for sustainable aquaculture feed. Frontiers Plant Science, 7, 440. doi:Doi: 10.3389/fpls.2016.00440
• Herman, E. M., Schmidt, M., He, Y., Erwin, C., Guo, J., Sun, R., Pendarvis, K., & Warner, B. (2016). Transgenic soybean production of bioactive human epidermal growth factor (EGF). PLOS One. doi:DOI:10.1371/journal.pone.0157034
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  Necrotizing enterocolitis (NEC) is a devastating condition of premature infants that results from the gut microbiome invading immature intestinal tissues. This results in a life-threaten- ing disease that is frequently treated with the surgical removal of diseased and dead tis- sues. Epidermal growth factor (EGF), typically found in bodily fluids, such as amniotic fluid, salvia and mother’s breast milk, is an intestinotrophic growth factor and may reduce the onset of NEC in premature infants. We have produced human EGF in soybean seeds to lev- els biologically relevant and demonstrated its comparable activity to commercially available EGF. Transgenic soybean seeds expressing a seed-specific codon optimized gene encod- ing of the human EGF protein with an added ER signal tag at the N’ terminal were produced. Seven independent lines were grown to homozygous and found to accumulate a range of 6.7 +/- 3.1 to 129.0 +/- 36.7 μg EGF/g of dry soybean seed. Proteomic and immunoblot anal- ysis indicates that the inserted EGF is the same as the human EGF protein. Phosphoryla- tion and immunohistochemical assays on the EGF receptor in HeLa cells indicate the EGF protein produced in soybean seed is bioactive and comparable to commercially available human EGF. This work demonstrates the feasibility of using soybean seeds as a biofactory to produce therapeutic agents in a soymilk delivery platform.

Presentations

• Herman, E. M. (2020, November). Enhancing soybean food and feed biosafety. Crop Science Society. on line: Crop Science Society.
• Herman, E. M. (2018, May). Remodeling Soybean Seed Protein Content and Composition. seminar. Ames Iowa: Pioneer (DuPont/Dow).
• Herman, E. M. (2018, October). Plants as the Monster. 200th Anniversary of the publication of Frankenstein. Arizona State U: Institue for Science and Global Policy.
• Herman, E. M. (2018, October). Remodeling soybeans for enhanced feed and food use. School of Animal and Comparative Biomedical Sciences seminar. UA: School of Animal and Comparative Biomedical Sciences.
• Herman, E. M. (2016, August). Engineering Altered Soybean Protein Composition and Content. 16th Biennial Conference of the Molecular and Cellular Biology of the Soybean. Columbus Ohio: 16th Biennial Conference of the Molecular and Cellular Biology of the Soybean.
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  Invited platform talk
• Herman, E. M. (2016, December). Remodeling the Soybean Seed Proteome -its Biology and Biotechnology. Seminar. USDA-Mericopa: USDA.
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  Academic seminar
• Herman, E. M. (2016, June). Remodeling the Soybean Seed Proteome -its Biology and Biotechnology. Seminar - UCSD. UCSD: UCSD.
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  Academic seminar

Poster Presentations

• Herman, E. M., & Schmidt, M. (2019, January). Altered expression of the ubiquitin E3 ring ligase AiP2 increases soybean seed protein content. PAG 2019. San Diego.
• Verla, M., Verla, M., Style, C., Style, C., Stoll, B., Stoll, B., Herman, E. M., Herman, E. M., Schmidt, M., Schmidt, M., Burrin, D., Burrin, D., Yu, L., Yu, L., Olutoye, O., & Olutoye, O. (2019, March). Efficacy of Soybean-derived Epidermal Growth Factor Therapy in the Preterm Piglet Model of Necrotizing Enterocolitis. American College of Surgeons 2019 Clinical CongressAmerican College of Surgeons.