Paul E Fenster
- Associate Professor, Medicine
Paul E. Fenster, MD, is an Associate Professor of Medicine. A native of New York, Dr. Fenster graduated cum laude from Brandeis University in 1970. He received his medical training at the State University of New York, Health Sciences Center at Brooklyn. After completing his internship in Internal Medicine at Brooklyn in 1975, he moved to Tucson. Following his residency in Internal Medicine at The University of Arizona College of Medicine, he completed a Cardiology Clinical Fellowship and Research Fellowship at The University of Arizona. He was a recipient of an American Heart Association Clinician-Scientist Award from 1980 to 1985 for the study of pharmacokinetic and dynamic effects of cardiac drugs.
Dr. Fenster received the Cardiology Fellowship Teaching Award in 1993,1998, and 2000.
Dr. Fenster is a Fellow of the American College of Cardiology. He is past President of the Arizona Affiliate of the American Heart Association, past President of the Southern Arizona Division of the American Heart Association, and past chairman of the Arizona Heart Association Research Advisory
He has authored over 41 original research publications, 35 book chapters, and 55 clinical reviews.
- State University of New York, Health Sciences Center at Brooklyn, New York, Brooklyn, New York, United States
- B.A. History
- Brandeis University, Waltham, Massachusetts, United States
- Cum Laude
- University of Arizona College of Medicine, Tucson, Arizona (1980 - 1985)
- University of Arizona College of Medicine, Tucson, Arizona (1979 - 1980)
- Cardiology Fellowship Teaching Award
- Spring 1998
- Spring 1993
- Spring 2000
Licensure & Certification
- Diplomate, American Board of Internal Medicine (1981)
- Arizona State Medical Doctor License #9636 (2016)
- Diplomate, American Board of Internal Medicine (1979)
- Diplomate, National Board of Medical Examiners (1975)
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- Suryanarayana, P., Fenster, P. E., Sorrell, V. L., & Jayasuriya, S. (2014). Mitral Stenosis. In Questions, Tricks, and Tips for the Echocardiography Boards(pp 105-112). Wolters Kluwer.
- Fenster, P. E., Sorrell, V. L., Fass, R., & Eslick, G. D. (2007). Evaluation of chest pain: A cardiology perspective for the Gastroenterologist.. In Noncardiac Chest Pain A Growing Medical Problem(pp 15-23). San Diego, CA: Plural Publishing Inc.
- Fenster, P. E. (2004). Evaluation of chest pain. In A cardiology perspective for gastroenterologists(pp 33-35-40). Gastroenterology Clinics of North America.
- Fenster, P. E., Sox, H. C., & Alpert, J. S. (2000). Ischemic heart disease: angina pectoris. In Scientific American Medicine. Healtheon/Web MD.
- Nies, A. S., Fenster, P. E., Hosenpud, J. D., & Greenberg, B. H. (2000). Clinical pharmacokinetics in congestive heart failure. In Congestive Heart Failure: Pathophysiology, Diagnosis and Comprehensive Approach to Management. 2nd Edition(pp 401-420). New York, NY: Lippincott, Williams & Wilkins.
- Butman, S. M., Fenster, P. E., Sethi, G., & Copeland, J. G. (1997, Summer). Is the right heart catheterization an anachronism in the evaluation of patients for thoracic organ transplantation?. European Society of CardiologyEuropean Society of Cardiology.More infoAbstract
- Wirth, R., Fenster, P. E., & Marcus, F. I. (1988. Transient heart block associated with head trauma(pp 262-4).More infoAtrioventricular nodal block is a rare consequence of head trauma. We report a case of a 63-year-old male with coronary artery disease who sustained a skull fracture. Twelve hours later the cardiac monitor recorded an episode of high-grade atrioventricular block with a ventricular escape rhythm. Subsequent electrophysiologic evaluation revealed no abnormality of atrioventricular nodal conduction nor of intraventricular conduction. Atrioventricular block after head trauma may be caused by enhanced vagal tone.
- Ring, M. E., & Fenster, P. E. (1986. Exercise-induced ST segment alternans(pp 1009-11).
- Kern, K. B., Temkin, L. P., & Fenster, P. E. (1983. Continuous intracoronary nitroglycerin infusion for spasm after angioplasty(pp 609-12).More infoA patient with reversible coronary artery spasm superimposed on fixed atherosclerotic coronary disease was treated with percutaneous transluminal angioplasty. The procedure successfully dilated the atherosclerotic lesion. However, 20 minutes later, the patient developed coronary artery spasm at the angioplasty site. Sublingual nitroglycerin, sublingual nifedipine, intravenous nitroglycerin, and repeated boluses of intracoronary nitroglycerin alleviated episodes of spasm, but failed to prevent recurrence. The patient was successfully treated with a continuous intracoronary infusion of nitroglycerin. Patients with coronary artery spasm in addition to fixed obstructive coronary disease may be at higher risk for spasm after percutaneous transluminal angioplasty. Continuous intracoronary infusion of nitroglycerin may be an effective therapy for recurrent coronary artery spasm occurring in the catheterization laboratory.
- Lancaster, L., & Fenster, P. E. (1983. Complete heart block after sublingual nitroglycerin(pp 111-2).More infoA 62-year-old man who was under observation following an episode of severe chest pain developed complete heart block and hypotension after receiving sublingual nitroglycerin. The reaction occurred while the patient was receiving an intravenous maintenance infusion of lidocaine but did not occur in response to either nitroglycerin alone or lidocaine alone. There was no evidence of acute cardiac ischemia nor of clinically significant underlying heart disease. Complete heart block after sublingual nitroglycerin in the absence of significant cardiac disease is an exceedingly rare phenomenon.
- Slepian, M. J., Weselcouch, E., Campbell, P. K., Roth, L., Massia, S. P., Dehdashti, B., Hilwig, R. W., Roeske, W. R., Fenster, P. E., & Kern, K. B. (1996, Spring). Complete In Vivo biodegradation of intracoronary drug delivery hydrogel polymers does not alter myocardial function.. Circulation 94:I-201,.
- Kern, K. B., Hilwig, R. W., Fenster, P. E., Berg, R. A., Sanders, A. B., Otto, C. W., & Ewy, G. A. (1993, Spring). Myocardial dysfunction following successful resuscitation.. Circulation 88:I-225.
- Eichhorn, E. J., DiBianco, R., Fenster, P. E., Tandon, P. K., Shannon, J., & Packer, M. (1992, Spring). Clinical and prognostic importance of serum magnesium concentration in patients with severe chronic heart failure.. J Am Coll Cardiol 19:254A,.
- Otto, M. D., Nolan, P. E., Hoyer, G. L., & Fenster, P. E. (1992, Spring). Characterization of amiodarone protein binding. Pharmacotherapy 12:245.
- Palmer, C. M., Fenster, P. E., Boswell, M. V., & Scipione, P. S. (1991, May). Echocardiographic evaluation of maternal myocardial function during Cesarean delivery under regional anesthesia.. Society for Obstetrical Anesthesia and Perinatology, May, 1990; and Anesthesiology 73:A938.
- Chesebro, J. H., Browne, K. F., Fenster, P. E., & Konstam, W. T. (1988, Spring). The hemodynamic effects of chronic oral milrinone therapy: a multicenter controlled trial.. J Am Coll Cardiol 11:144A.
- Nolan, P. E., Armstrong, E. P., Charland, S. L., Fenster, P. E., & Kipps, J. E. (1988, Spring). Effect of diet on the absorption of sustained-release procainamide. Pharmacotherapy 8:118.
- Ring, M. E., Corrigan, J. J., & Fenster, P. E. (1987, Spring). Antiplatelet effects of oral diltiazem, propranolol and their combination. Clin Res 35: 116A.
- Nolan, P., Mayersohn, M., Fenster, P. E., Bliss, M., & Quan, S. (1986, Spring). Pharmacokinetic comparison of single dose and chronically dosed amiodarone in healthy volunteers.. Acta Pharmacol Toxicol 59(Supp. V):40,.
- Fenster, P. E., & White, N. W. (1984, Spring). Pharmacokinetic evaluation of the digoxin- amiodarone interaction. J Am Coll Cardiol 3:567.
- Fenster, P. E., MacFarland, R. T., Graves, P. E., Perrier, D., & Marcus, F. I. (1985, Spring). Bioavailability of digitoxin, digitoxigenin bisdigitoxoside and digitoxigenin monodigitoxoside by a specific assay.. Clin Res 33: 20A.
- Nolan, P. E., Mayersohn, M., Fenster, P. E., & Bliss, M. (1985, Spring). Single-dose pharmacokinetics of amiodarone. Drug Intelligence and Clinical Pharmacy 19:463.
- Fenster, P. E., & Hanson, C. D. (1983, Spring). Double blind comparison of mexiletine and quinidine in the treatment of ventricular ectopy. Clin Res 31:19A.
- Fenster, P. E., Reynolds, D., Morrison, D., Horwitz, L., Goldman, S., Thadani, R., Lazzara, R., & Marcus, F. (1984, Spring). Atenolol for ventricular ectopy and nonsustained ventricular tachycardia: A dose response study.. Clin Res 32:5A.
- Graves, P., Fenster, P. E., MacFarland, R. T., Marcus, F. I., & Perrier, D. (1984, Spring). Pharmacokinetics of digitoxin, digitoxigenin bisdigitoxoside and digitoxigenin monodigitoxoside in normal and azotemic subjects.. IUPHAR 9th International Congress of Pharmacology: 29P.
- White, N., & Fenster, P. E. (1984, Spring). Pharmacokinetic evaluation of the digoxin-amiodarone interaction. J Am Coll Cardiol 3:567.
- Fenster, P. E., & Hanson, C. D. (1983, Spring). Comparison of quinidine and mexiletine in treatment of chronic ventricular ectopy.. Clin Pharmacol Ther 33:205.
- Fenster, P. E., & Kern, K. B. (1983, Spring). Mexiletine treatment of refractory ventricular arrhythmia. Clin Res 31:7A.
- Kern, K. B., & Fenster, P. E. (1983, Spring). Clinical experience with mexiletine in the treatment of refractory ventricular arrhythmias.. Clin Res 31:195A.
- Fenster, P. E., & Dahl, C. (1982, Spring). Comparison of quinidine and mexiletine in the treatment of chronic ventricular ectopy.. Clin Res 30: 7A.
- Fenster, P. E., Hager, W. D., & Powell, J. R. (1982, Spring). Digoxin-quinidine interaction in renal failure patients on hemodialysis: insight into mechanism.. Am J Cardiol 49: 1026.
- Fenster, P. E., Hager, W. D., & Powell, J. R. (1982, Spring). Effect of renal failure on the digoxin-quinidine interaction. Clin Res 30:25A.
- Fenster, P. E., Quan, S., Hanson, C. D., & Coaker, L. (1982, Spring). Oral metoprolol therapy of dysrhythmias in chronic obstructive pulmonary disease.. Clin Res 30.
- Fenster, P. E., Serokman, R., Comess, K., Hanson, C. D., & Moon, T. (1982, Spring). Relationship between suppression of frequency of ventricular ectopy and suppression of complex forms. Clin Res 30: 185A.
- Quan, S., Fenster, P. E., Hanson, C. D., & Coaker, L. (1982, Spring). Treatment of atrial and ventricular arrhythmias with intravenous metoprolol in patients with COPD. Clin Res 30: 214A.
- Fenster, P. E., Dahl, C., Ewy, G. A., & Marcus, F. I. (1981, Spring). Quinidine depression of the blood pressure response to treadmill exercise.. Clin Res 29:6A.
- Abraham, T., Hanson, F., Fenster, P. E., & Marcus, F. I. (1981, Spring). Effect of Intravenous metoprolol on pulmonary function in chronic airways obstruction. Amer Rev Resp Dis 121:105,.
- Fenster, P. E., Powell, J. R., Graves, P. E., Conrad, K. A., & Goldman, S. (1980, Spring). Combined digitoxin-quinidine administration: pharmacokinetic evaluation. Clin Res 28:235A.
- Fenster, P. E., Powell, J. R., Hager, W. D., Graves, P., & Conrad, K. (1980, Spring). Onset and dose dependence of the digoxin-quinidine interaction.. Am J Cardiol 45:413.
- Powell, R., Fenster, P. E., Hager, W. D., Wandell, M., Hager, D., Graves, P., Conrad, K., & Goldman, S. (1980, Spring). Digoxin-quinidine interaction: Multiple dose pharmacokinetics. Clin Pharmacol Ther 27:279.
- Devlin, R. G., Vukovich, R. A., Marcus, F. I., & Fenster, P. E. (1979, Spring). Analysis of serum concentration and efficacy in cardiodysrhythmic patients administered sustained-release procainamide tablets.. Clin Pharmacol Ther 25:221.
- Fenster, P. E., Giardina, E. V., Bigger, J. T., Marcus, F. I., Mayersohn, M., & Perrier, D. (1979, Spring). Efficacy and kinetics of a new sustained-release procainamide preparation. Circulation 60 Suppl II: II-84.
- Hager, W. D., Fenster, P. E., Mayersohn, M., Perrier, D. G., Graves, P. E., & Marcus, F. I. (1979, Spring). Digoxin-quinidine interaction: Pharmacokinetic evaluation. Clin Res 27(2): 233A.
- Powell, J. R., Wandell, M., Fenster, P. E., Hager, D., Goldman, S., & Conrad, K. (1979, Spring). Quinine effect on digoxin kinetics in humans. Pharmacologist 21:169.