Rebecca Marie Thiede

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Journals/Publications

• Fernandez, J. M., Koblinski, J. E., Dahak, S., Curiel-Lewandrowski, C., & Thiede, R. (2024). Gender differences in pediatric and adolescent melanoma: A retrospective analysis of 4645 cases. Journal of the American Academy of Dermatology, 90(2), 280-287.
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  There is paucity of data on how gender impacts melanoma prognosis in pediatric and adolescent patients.
• Godfrey, H., Jedlowski, P., & Thiede, R. (2024). Medication Associations with Severe Cutaneous Adverse Reactions: A Case/Non-Case Analysis Using the FDA Adverse Event Reporting System. Journal of cutaneous medicine and surgery, 12034754231220931.
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  Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP) are potentially life-threatening severe cutaneous adverse reactions (SCARs). Although the classical causal agents of SCARs (antibiotics, anticonvulsants, nonsteroidal anti-inflammatory drugs, and allopurinol) are well characterized, there has been little update to this list to account for newly marketed medications.
• Dagenet, C. B., Davis, M. S., Murphy, S., Thiede, R., Culpepper, K. S., & Fazel, M. (2023). Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on Leg, Tucson, Arizona, USA. Emerging infectious diseases, 29(6), 1268-1269.
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  We report a 34-year-old man who had a nonhealing, verrucous plaque with central ulceration on the lower leg. This case-patient is a rare example of endemic limited cutaneous leishmaniasis in Tucson, Arizona, USA. Clinicians should be aware of this disease because its manifestations can vary for individual patients.
• Godfrey, H., Leibovit-Reiben, Z., & Thiede, R. (2023). Skin through the lens of Rembrandt van Rijn. Journal of the European Academy of Dermatology and Venereology : JEADV, 37(12), 2413-2414.
• Kelly, B. G., Forbes, B. R., & Thiede, R. M. (2022). Late-onset systemic lupus erythematosus associated with inverse discoid lupus erythematosus on the buttock. JAAD case reports, 24, 115-117.
• Thiede, R. M., Fazel, M., MacDonald, K. M., & Abraham, I. (2022). Does synthetic pharmacotherapy still have a place in treating chronic spontaneous urticaria?. Expert opinion on pharmacotherapy, 23(14), 1563-1567.
• Price, K. N., Thiede, R., Shi, V. Y., & Curiel-Lewandrowski, C. (2020). Strategic dermatology clinical operations during the coronavirus disease 2019 (COVID-19) pandemic. Journal of the American Academy of Dermatology, 82(6), e207-e209.
• Rastogi, S., Thiede, R., Sadowsky, L. M., Hua, T., Rastogi, A., Miller, C., & Schlosser, B. J. (2019). Sex Differences in Initial Treatment for Genital Extramammary Paget's Disease in the United States: A Systematic Review. Journal of the American Academy of Dermatology.
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  Surgery is the standard treatment for genital extramammary Paget's disease (gEMPD).
• Sadowsky, L. M., Thareja, S., Thiede, R., Nardone, B., West, D. P., Schlosser, B. J., & Rangel, S. M. (2019). 572 Development and validation of a vulvar scarring severity scale for assessment of lichen sclerosus. Journal of Investigative Dermatology, 139(5), S98. doi:10.1016/j.jid.2019.03.648
• Thiede, R. M., Rastogi, S., Nardone, B., Sadowsky, L. M., Rangel, S. M., West, D. P., & Schlosser, B. J. (2019). Hyperkalemia in women with acne exposed to oral spironolactone: A retrospective study from the RADAR (Research on Adverse Drug Events and Reports) program. International journal of women's dermatology, 5(3), 155-157.
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  The necessity of serum potassium monitoring for healthy women who are prescribed spironolactone for acne has been debated. The aim of this study was to compare the incidence of hyperkalemia in women 18 to 45 years of age to that in women 46 to 65 years of age, when treated with oral spironolactone for acne.
• Ibler, E., Tran, G., Orrell, K. A., Serrano, L., Majewski, S., Sable, K. A., Thiede, R., Laumann, A. E., West, D. P., & Nardone, B. (2018). Inverse association for diagnosis of Alzheimer's disease subsequent to both melanoma and non-melanoma skin cancers in a large, urban, single-centre, Midwestern US patient population. Journal of the European Academy of Dermatology and Venereology : JEADV, 32(11), 1893-1896.
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  Although literature demonstrates a decreased risk of Alzheimer's disease (AD) in individuals with various cancers, including squamous cell cancers (SCC) and basal cell cancers (BCC) comprising non-melanoma skin cancers (NMSC), there is a paucity of literature to substantiate an association between malignant melanoma (MM) and AD.
• Thiede, R., Rastogi, S., Nardone, B., West, D. P., Rangel, S. M., & Schlosser, B. J. (2018). LB1516 Hyperkalemia in women with acne exposed to spironolactone in a large, urban, Midwestern U.S. population: A report from the Research on Adverse Drug Events and Reports Program (RADAR). Journal of Investigative Dermatology, 138(9), B8. doi:10.1016/j.jid.2018.06.047
• Beskind, D. L., Stolz, U., Thiede, R., Hoyer, R., Robertson, W., Brown, J., Ludgate, M., Tiutan, T., Shane, R., McMorrow, D., Pleasants, M., Kern, K. B., & Panchal, A. R. (2017). Viewing an ultra-brief chest compression only video improves some measures of bystander CPR performance and responsiveness at a mass gathering event. Resuscitation, 118, 96-100.
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  CPR training at mass gathering events is an important part of health initiatives to improve cardiac arrest survival. However, it is unclear whether training lay bystanders using an ultra-brief video at a mass gathering event improves CPR quality and responsiveness.
• Lewandowski, K. T., Thiede, R., Guido, N., Daniel, W. L., Kang, R., Guerrero-Zayas, M. I., Seeger, M. A., Wang, X. Q., Giljohann, D. A., & Paller, A. S. (2017). Topically Delivered Tumor Necrosis Factor-α-Targeted Gene Regulation for Psoriasis. The Journal of investigative dermatology, 137(9), 2027-2030.
• Beskind, D. L., Stolz, U., Thiede, R., Hoyer, R., Burns, W., Brown, J., Ludgate, M., Tiutan, T., Shane, R., McMorrow, D., Pleasants, M., & Panchal, A. R. (2016). Viewing a brief chest-compression-only CPR video improves bystander CPR performance and responsiveness in high school students: A cluster randomized trial. Resuscitation, 104, 28-33.
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  CPR training in schools is a public health initiative to improve out of hospital cardiac arrest (OHCA) survival. It is unclear whether brief video training in students improves CPR quality and responsiveness and skills retention.
• Thiede, R., Toosizadeh, N., Mills, J. L., Zaky, M., Mohler, J., & Najafi, B. (2016). Gait and balance assessments as early indicators of frailty in patients with known peripheral artery disease. Clinical biomechanics (Bristol, Avon), 32, 1-7.
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  Peripheral artery disease is associated with increased morbidity and mortality, and frailty syndrome may mediate the risk of these adverse health outcomes to predict intervention results. The aim of this study was to determine the association between motor performance impairments based on in-clinic gait and balance measurements with frailty at intermediate stages (pre-frailty) in peripheral artery disease patients.
• Toosizadeh, N., Stocker, H., Thiede, R., Mohler, J., Mills, J. L., & Najafi, B. (2016). Alterations in gait parameters with peripheral artery disease: The importance of pre-frailty as a confounding variable. Vascular medicine (London, England), 21(6), 520-527.
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  Although poor walking is the most common symptom of peripheral artery disease (PAD), reported results are inconsistent when comparing gait parameters between PAD patients and healthy controls. This inconsistency may be due to frailty, which is highly prevalent among PAD patients. To address this hypothesis, 41 participants, 17 PAD (74±8 years) and 24 aged-matched controls (76±7 years), were recruited. Gait was objectively assessed using validated wearable sensors. Analysis of covariate (ANCOVA) tests were used to compare gait parameters between PAD and non-PAD groups, considering age, gender, and body mass index as covariates, while stratified based on frailty status. According to the Fried frailty index, 47% of PAD and 50% of control participants were non-frail and the rest were classified as pre-frail. Within non-frail participants, gait speed, body sway during walking, stride length, gait cycle time, double-support, knee range of motion, speed variability, mid-swing speed, and gait initiation were significantly different between PAD and control groups (effect size d = 0.75±0.43). In the pre-frail group, however, most of the gait differences were diminished except for gait initiation and gait variability. Results suggest that gait initiation is the most sensitive parameter for detecting gait impairment in PAD participants when compared to controls, regardless of frailty status (d = 1.30-1.41; p
• Thiede, R. M., Lu, Y., & Markel, M. D. (2012). A review of the treatment methods for cartilage defects. Veterinary and comparative orthopaedics and traumatology : V.C.O.T, 25(4), 263-72.
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  The purpose of this article is to provide a broad review of the literature related to the treatment of cartilage defects and degenerated cartilage in animals with some inferences to the treatment in humans. Methods range from the insertion of osteochondral tissue or cells to the application of radio frequency or insertion of scaffolds and growth factors alone or in combination. Debridement, microfracture, radio frequency, and chondrocyte implantation are all methods normally utilized when treating smaller articular cartilage defects. Scaffolds and mosaicplasty are examples of methods to treat larger defects. This review will cover all major treatment methods currently used to treat articular cartilage defects.