Sunil K Sinha
- Assistant Clinical Professor, Pediatrics - (Clinical Series Track)
Contact
- (520) 626-5585
- Arizona Health Sciences Center, Rm. 3301
- sinhas@arizona.edu
Biography
Chapters in Scholarly Books
- Sunil K Sinha, Rohan K Henry, Manmohan K Kamboj. Diabetes mellitus in children and adolescents. Int J Child Health Hum Dev Vol. 13, Iss.1, (2020): 33-49
- Sunil K Sinha, Alicia Diaz-Thomas. Endocrinopathies associated with Noonan syndrome. Noonan Syndrome: Characteristics and Interventions. June 2019. Publisher: Elsevier Science. Editor. Amrit Bhangoo.
Refereed Journal articles - Peer Reviewed
- John Anthonypillai, Sunil K Sinha, Andrey Mamkin, Svetlana Ten, Qing Dong, Amrit Bhangoo. Experience with cinacalcet in familial hypocalciuric hypercalcemia resulting from inactivating mutations in calcium sensing receptor (CaSR). Endocrinol Metab Int J. 2018;6(2):137‒ DOI:10.15406/emij.2018.06.00167
- Nouhad Raissouni, Andrey Kolesnikov, Radhika Purushothaman, Sunil Sinha, Sonal Bhandari, Amrit Bhangoo, Shahid Malik, Revi Mathew, Jean-Patrice Baillargeon, Isabel M Hernandez, Michael Rosenbaum, Svetlana Ten and David Geller. Altered Glucose Disposition and Insulin Sensitivity in Peri-pubertal First-Degree Relatives of Women with Polycystic Ovary Syndrome. Int J Pediatr Endocrinol. 2012; 2012:14.
- Philibert P, Paris F, Audran F, Kalfa N, Polak M, Thibaud E, Pinto G, Houang M, Zenaty D, Leger J, Mas JC, Pienkowski C, Einaudi S, Damiani D, Ten S, Sinha S, Poulat F, Sultan C. Phenotypic Variation of SF1 Gene Mutations. Adv Exp Med Biol. 2011;707:67-72.
- Sinha SK, Pascal Philibert, Charles Sultan and Svetlana Ten: Inguinal hernia in a phenotypic female infant may reveal a 46XY sex reversal, supported by the identification of a novel SF1 gene mutation. Adv Exp Med Biol. 2011;707:149-50.
- Sinha SK, Amrit Bhangoo, Svetlana Ten, and Joerg Gromoll. Leydig Cell Hypoplasia due to Inactivating Luteinizing Hormone/Chorionic Gonadotropin Receptor Gene Mutation Presenting as a 46,XY DSD. Adv Exp Med Biol. 2011;707:147-8.
- Bhangoo A, Sinha SK, Ten S. Pubertal Advancement Improves Endothelial Function as Measured by Peripheral Arterial Tonometry (PAT). Horm Res Paediatrics: 2011;76(4):226-33.
- George M, Sinha S, Mamkin I, Philibert P, New M, Wilson RC, Sultan C, Ten S, Bhangoo, A. Isolated Mild Clitoral Hypertrophy May Reveal 46,XY disorders of sex development in Infancy due to 17βHSD-3 Defect Confirmed by Molecular Analysis. Gynecological Endocrinology 2011;27:890-4.
- Derr MA, Fang P, Sinha SK, Ten S, Hwa V, Rosenfeld RG. A novel Y332C missense mutation in the intracellular domain of the human growth hormone receptor does not alter STAT5b signaling: redundancy of GHR intracellular tyrosines involved in STAT5b signaling. Horm Res Paediatr. 2011;75(3):187-99
- Alatzoglou KS, Turton JP, Kelberman D, Clayton PE, Mehta A, Buchanan C, Aylwin S, Crowne EC, Christesen HT, Hertel NT, Trainer PJ, Savage MO, Raza J, Banerjee K, Sinha SK, Ten S, Mushtaq T, Brauner R, Cheetham TD, Hindmarsh PC, Mullis PE, Dattani MT. Expanding the spectrum of mutations in GH1 and GHRHR: genetic screening in a large cohort of patients with congenital isolated growth hormone deficiency. JCEM. 2009 Sep;94(9):3191-9
- Zhou P, Ten S, Sinha S, Ramchandani N, Vogiatzi M, Maclaren N. Insulin receptor autoimmunity and insulin resistance. JPEM. 2008 Apr;21(4):369-75.
- Sinha SK, Amrit Bhangoo, Henry Anhalt, Noel Maclaren, Jan D. Marshall, Gayle B.Collin, Jurgen K Naggert and Svetlana Effect of Metformin and Rosiglitazone in a Prepubertal Boy with Alström Syndrome. JPEM 2007 Sep;20(9):1045-52.
- Motaghedi R, Gujral S, Sinha S, Sison C, Ten S, Maclaren NK. Insulin-like growth factor binding protein-1 to screen for insulin resistance in children. Diabetes Technol Ther. 2007 Feb;9(1):43-51.
- Ramchandani N, Ten S, Anhalt H, Sinha S, Ching J, Finkelstein A, Maclaren NK. Insulin pump therapy from the time of diagnosis of type 1 diabetes. Diabetes Technol Ther. 2006 Dec;8(6): 663-70.
- Anjli Kukerja, Guilia Costi, John Marker, Chen Hui Zhang, Sinha S and Noel Maclaren. NKT Cell defects in NOD Mice suggest therapeutic opportunities. J Autoimmunity (2002) 19, 117-128.
Degrees
- M.B.B.S.
- Rajshahi Medical College, Rajshahi, Bangladesh
Work Experience
- Maimonides Children’s Hospital (2008 - 2011)
- SUNY Downstate College of Medicine (2005 - 2008)
Licensure & Certification
- Pediatric Endocrinology, American Academy of Pediatrics (2021)
- Pediatrics (2017)
Interests
No activities entered.
Courses
2024-25 Courses
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Pediatric Endocrinology
PED 850P (Fall 2024)
2023-24 Courses
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Pediatric Endocrinology
PED 850P (Fall 2023)
2021-22 Courses
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Pediatric Endocrinology
PED 850P (Fall 2021)
2020-21 Courses
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Pediatric Endocrinology
PED 850P (Spring 2021)
Scholarly Contributions
Chapters
- Sinha, S. (2020). Diabetes Mellitus in Children and Adolescents. In Chronic Disease and Disability: The Pediatric Liver(pp 33-49). Nova Science Publishers, Inc.
Journals/Publications
- Raissouni, N., Kolesnikov, A., Purushothaman, R., Sinha, S., Bhandari, S., Bhangoo, A., Malik, S., Baillargeon, J., Hernandez, M. I., Rosenbaum, M., Ten, S., Mathew, R. P., & Geller, D. H. (2012). Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome.. International journal of pediatric endocrinology, 2012(1), 14. doi:10.1186/1687-9856-2012-14More infoFirst-degree relatives (FDRs) of women with PCOS are at increased risk for impaired insulin sensitivity and diabetes mellitus. Glucose tolerant FDR have evidence of insulin resistance and hyperinsulinemia prior to emergence of frank PCOS..To study insulin dynamics parameters in the early adolescent FDR of women with PCOS..This is a cross-sectional study involving 18 adolescents whose mothers or sisters had been diagnosed with PCOS and 21 healthy, age-matched control adolescents without FDR. Subjects underwent anthropometric measurements, steroid profiling and frequently sampled Intravenous Glucose Tolerance Test (IVGTT), Homeostasis Model Assessment (HOMA) index, Glucose Disposal Index (GDI), Acute Insulin Response (AIR) and Quantitative insulin sensitivity check index (QUICKI) were derived from IVGTT results..FDRs showed significantly higher mean HOMA and lower GDI. There were no differences in mean age or BMI Z-score between the cohorts. No differences in sex steroids or AIR were identified between groups..Female adolescent FDR of women with PCOS have higher HOMA index and lower QUICKI, reflecting altered insulin sensitivity and lower GDI reflecting poorer beta-cell function. The presence of multiple risk factors for type 2 diabetes suggests that aggressive screening of the early adolescent FDR of women with PCOS is indicated.
Poster Presentations
- Sinha, S. (2019, October). Continuous glucose monitoring and continuous insulin infusion via pump decrease diabetes related distress (DRD) and depression screening score in adolescents with type 1 diabetes.. 45th Annual ISPAD Conference. Boston, USA: ISPAD.
