Justin Hayes

Interests

Teaching

I have an interest in providing innovative antimicrobial stewardship educational sessions for internal medicine residents and infectious diseases fellows as well as implementing dynamic board review sessions in medical education.

Research

I am interested in the rapid diagnosis of pathogens to improve antimicrobial stewardship metrics and clinical outcomes. I am also interested in interventions designed to limit unnecessary antimicrobial use as well unnecessary diagnostic testing.

Courses

No activities entered.

Scholarly Contributions

Chapters

• Hayes, J., & Baddley, J. W. (2020). Respiratory Infections. In Comprehensive Review of Infectious Diseases.
• Hayes, J., & Lee, R. A. (2020). Infection Control and Prevention. In Comprehensive Review of Infectious Diseases.

Journals/Publications

• Nix, D. E., Hayes, J. F., Al Obaidi, M., & Zangeneh, T. (2020). Fixed Dosing of Amphotericin B in Morbidly Obese Individuals. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
• Hayes, J. F., Lee, R. A., & Camins, B. C. (2018). 506. The Impact of Bowel Management System (BMS) on the Incidence of Hospital-Onset (HO) Clostridium difficile Infection Laboratory-ID Events Despite Diagnostic Stewardship. Open Forum Infectious Diseases, 5(suppl_1), S187-S187. doi:10.1093/ofid/ofy210.515
• Hayes, J., & Nellore, A. (2018). Management of Strongyloides in Solid Organ Transplant Recipients. Infectious disease clinics of North America, 32(3), 749-763.
  More info

  Strongyloides stercoralis is a threadworm parasite with the unique capacity to complete its entire life cycle in a human host. Although asymptomatic in normal hosts, S stercoralis infection in solid organ transplant recipients is often severe, disseminated, and fatal. Risk factors for disease acquisition include travel to endemic regions. Antihelminth therapy should be instituted before transplantation for optimal clinical outcomes. Herein we review the epidemiology, biology, immune response, and diagnostic and screening strategies, as well as treatment modalities for S stercoralis in the solid organ transplant population.
• Hayes, J. F., Turner, O. D., Mccarty, T. P., Manning, M., Hoesley, C. J., & Pappas, P. G. (2017). Influence of T2 Candida Testing for Rapid Diagnosis of Candida Infections on Antifungal Stewardship Efforts at a Large Academic Medical Center: A Retrospective, Single-center Study. Open Forum Infectious Diseases, 4(suppl_1), S628-S628. doi:10.1093/ofid/ofx163.1667
• Turner, O. D., Hayes, J. F., Mccarty, T. P., Manning, M., Hoesley, C. J., & Pappas, P. G. (2017). Relationship of T2 Candida Panel to Disease Severity, Mortality and Time to Therapy in Patients with Candidemia. Open Forum Infectious Diseases, 4(suppl_1), S609-S609. doi:10.1093/ofid/ofx163.1597
• Musto, A. E., Samii, M. S., & Hayes, J. F. (2009). Different phases of afterdischarge during rapid kindling procedure in mice. Epilepsy research, 85(2-3), 199-205.
  More info

  The basic mechanisms of hippocampal networks in epileptogenesis are not entirely understood. To help achieve a better understanding of these mechanisms, we studied the extra-cellular electrically evoked responses in the hippocampi of mice during rapid kindling. Kindling protocol was achieved by stimulating the dorsal right hippocampus six times daily for four days using bipolar electrodes to produce sub-convulsive electrical discharges. Motor responses and analyzed electroencephalographic recordings showed progression from partial complex seizures to generalized seizures associated with different consecutive patterns within the afterdischarges. A spike-wave pattern appeared immediately after stimulation in combination with a poly-spike complex superimposed over the wave (AD1). AD1 was followed by a poly-spike complex (AD2), which was followed by a progressive modification of repetitive spikes (AD3). An ictal depression event was observed at the end of each AD3. Theta oscillations were observed at stage 1-2 of kindling, while beta/gamma oscillations appeared within AD2, associated with stage 4-5 from Racine's score. Benzodiazepine, a GABA (A) agonist (Diazepam) administered at non-sedative doses and only on days 3 and 4 of kindling, limited beta and gamma frequency bands and the progression of seizure severity, suggesting that the failure of GABA (A) agonism mediates the propagation or generalization of seizures. We conclude that different phases of afterdischarge occur during kindling and that high frequencies mediate generalization of seizures.

Presentations

• Hayes, J. (2021). MSG-15: Clinical outcomes data from an open label randomized clinical trial comparing oral SUBAitraconazole (SUBAITRA) to conventional itraconazole (C-ITRA) for treatment of endemic mycosis.. European Congress of Clinical Microbiology and Infectious Diseases.
• Hayes, J. (2021). MSG-15: Pharmacokinetic, Adverse Events, and Tolerability Data From an Open-Label Randomized Trial Comparing Oral SUBAItraconazole to Conventional Itraconazole for Treatment of Endemic Mycoses.. European Congress of Clinical Microbiology and Infectious Diseases.
• Hayes, J. (2021). SUBA itraconazole (SUBA) versus conventional itraconazole (C-ITRA) for treatment of endemic mycoses: summary of clinical results (MSG-15).. Trends in Medical Mycology.
• Hayes, J. (2020, October). MSG-15: Pharmacokinetic (PK), Adverse Events (AEs), and Tolerability Data from an Open Label Randomized Clinical Trial (RCT) Comparing Oral Suba-itraconazole(SUBA-ITC) to Conventional Itraconazole(C-ITC) for Treatment of Endemic Mycosis (EM). IDWeek 2020. Virtual IDWeek 2020: Infectious Diseases Society of America.

Poster Presentations

• Hayes, J., Nix, D. E., Matthias, K. R., Villanueva, J. E., Matthias, K. R., Villanueva, J. E., Hayes, J., & Nix, D. E. (2020, Oct). A Descriptive Analysis of Fluconazole Utilization at Two Academic Medical Centers in the Valley Fever Corridor of Arizona. IDWeek 2020. Virtual conference: Infectious Diseases Society of America.
• Hayes, J. (2018, Fall 2018). The Impact of Bowel Management System on the Incidence of Hospital-Onset Clostridium difficile Infection Laboratory-ID Events Despite Diagnostic Stewardship. IDWeek 2018. San Francisco.
• Hayes, J., Turner, O., McCarty, T., Manning, M., Hoesley, C., & Pappas, P. (2017, October). Influence of T2Candida testing for rapid diagnosis of Candida infections on antifungal stewardship efforts at a large academic medical center: a retrospective, single-center study.. IDWeek 2017. San Diego, CA.

Others

• Hayes, J., Lee, R. A., & Camins, B. (2018, December). The Impact of Bowel Management System (BMS) on the Incidence of Hospital-Onset (HO) Clostridium difficile Infection Laboratory-ID Events despite Diagnostic Stewardship. Open Forum Infectious Diseases.
• Hayes, J., Turner, O. D., McCarty, T. P., Manning, M., Hoesley, C. J., & Pappas, P. G. (2017, April). Influence of T2Candida testing for rapid diagnosis of Candida infections on antifunal stewardship efforts at a large academic medical center: a retrospective, single-center study.. Open Forum Infectious Diseases.
• Hayes, J., Turner, O. D., McCarty, T. P., Manning, M., Hoesley, C. J., & Pappas, P. G. (2017, April). Relationship of T2Candida Panel to Disease Severity, Mortality and Time to Therapy in Patients with Candidemia. Open Forum of Infectious Diseases.