Lisa M Grimaldi

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Scholarly Contributions

Journals/Publications

• Grimaldi, L., Gradidge, E., Mastropietro, C. M., Cashen, K., Wilhelm, M., Piggott, K., Costello, J., & Gowda, K. (2018). Near Infrared Spectroscopy for Prediction of Extubation Success after Neonatal Cardiac Surgery. Cardiology in the Young.
• Wong, R. J., Mruk, A. L., Grimaldi, L. M., Patel, R., Mirea, L., & Engelhardt, K. P. (2024). Nicardipine or Nitroprusside for Postoperative Blood Pressure Control in Infants After Surgery for Congenital Heart Disease: Single-Center Retrospective Noninferiority and Cost Analysis, 2016–2020. Pediatric Critical Care Medicine. doi:10.1097/pcc.0000000000003469
• Grimaldi, L. M., Cashen, K., Costello, J. M., Gowda, K. M., Gradidge, E. A., Mastropietro, C. W., Piggott, K. D., & Wilhelm, M. (2019). Near-infrared spectroscopy for prediction of extubation success after neonatal cardiac surgery.. Cardiology in the young, 29(6), 787-792. doi:10.1017/s1047951119000829
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  Reliable predictors of extubation readiness are needed and may reduce morbidity related to extubation failure. We aimed to examine the relationship between changes in pre-extubation near-infrared spectroscopy measurements from baseline and extubation outcomes after neonatal cardiac surgery..In this retrospective cross-sectional multi-centre study, a secondary analysis of prospectively collected data from neonates who underwent cardiac surgery at seven tertiary-care children's hospitals in 2015 was performed. Extubation failure was defined as need for re-intubation within 72 hours of the first planned extubation attempt. Near-infrared spectroscopy measurements obtained before surgery and before extubation in patients who failed extubation were compared to those of patients who extubated successfully using t-tests..Near-infrared spectroscopy measurements were available for 159 neonates, including 52 with single ventricle physiology. Median age at surgery was 6 days (range: 1-29 days). A total of 15 patients (9.4 %) failed extubation. Baseline cerebral and renal near-infrared spectroscopy measurements were not statistically different between those who were successfully extubated and those who failed, but pre-extubation cerebral and renal values were significantly higher in neonates who extubated successfully. An increase from baseline to time of extubation values in cerebral oximetry saturation by ≥ 5 % had a positive predictive value for extubation success of 98.6 % (95%CI: 91.1-99.8 %)..Pre-extubation cerebral near-infrared spectroscopy measurements, when compared to baseline, were significantly associated with extubation outcomes. These findings demonstrate the potential of this tool as a valuable adjunct in assessing extubation readiness after paediatric cardiac surgery and warrant further evaluation in a larger prospective study.
• Grimaldi, L., Hu, C., Kang, P., & Kaib, S. (2018). Mock interviews with video-stimulated recall to prepare medical students for residency interviews. AMEE MedEdPublish. doi:doi.org/10.15694/mep.2018.0000168.1
• Grimaldi, L., Wilhelm, M., Mastropietro, C., Costello, J., Piggott, K., Cashen, K., Gowda, K., & Moser, E. (2018). Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery. Pediatric Critical Care Medicine, 19(11), 1015-1023.
• McCartan, S., Paul, K., Hu, C., & Grimaldi, L. (2018). Mock interviews with video-stimulated recall to prepare medical students for residency interviews. AMEE MedEdPublish. doi:https://doi.org/10.15694/mep.2018.0000168.1

Presentations

• Gradidge, E., Cashen, K., Gowda, K., Piggott, K., Wilhelm, M., Costello, J., Mastropietro, C., & Grimaldi, L. (2017, July). Use of Near Infrared Spectroscopy to Predict Extubation Success in Neonates after Cardiac Surgery. World Congress of Pediatric Cardiology and Cardiac Surgery Conference. Barcelona, Spain.
• Grimaldi, L., Perez, S., Michaelsen, R., & Niggemann, E. (2017, February). “Choose Your Own Shock Adventure”: An Interactive Module for First Year Medical Students. USC Innovations in Medical Education Conference.