Linnea Linde-Krieger

Interests

Research

Normative and atypical responses to adversity; Substance misuse during the perinatal period;Caregiving and attachment; Prevention and intervention programming;Stress physiology and health; Quantitative methods;Developmental psychopathology; Harm reduction policy and practice;

Teaching

Maternal-child health;Lifespan development;Developmental psychopathology;Resilience following adversity;Substance use disorders;Health disparities;Feminist pedagogy

Courses

Scholarly Contributions

Chapters

• Linde-Krieger, L. B., Yates, T. M., Carlson, E. E., Dorahy, M. J., Gold, S. N., & O'Neil, J. A. (2022). A Developmental Pathways Model of Dissociation. In Dissociation and the Dissociative Disorders, 2nd Ed.(p. 12). Routledge. doi:https://doi.org/10.4324/9781003057314

Journals/Publications

• Linde-Krieger, L. B., Rudd, K. L., Aringer, A. S., & Yates, T. M. (2024). A Longitudinal Investigation of Caregiving and Adolescent Psychological Stress Symptoms during COVID-19: Evidence for High Resting RSA as a Susceptibility Factor. Psychological Medicine.
• MacLean, E. L., Carranza, E., Gnanadesikan, G. E., King, K. M., Allen, A. M., Linde-Krieger, L. B., Feldman, R., White-Traut, R. C., Hammock, E. A., Carter, C. S., Leng, G., Tecot, S. R., & Bell, A. F. (2024). Neurophysin I is an analytically robust surrogate biomarker for oxytocin. Psychoneuroendocrinology, 161, 106951.
  More info

  Oxytocin is a pleiotropic neuropeptide that plays roles in biological processes ranging from birth, lactation, and social bonding to immune function, cardiovascular repair, and regulation of appetite. Although measurements of endogenous oxytocin concentrations have been performed for more than 50 years, the ability to measure oxytocin accurately poses notable challenges. One potential solution for overcoming these challenges involves measurement of oxytocin's carrier molecule - neurophysin I (NP-1) - as a surrogate biomarker. NP-1 is secreted in equimolar concentrations with oxytocin but has a longer half-life, circulates in higher concentrations, and can be measured using a sandwich immunoassay. We report experiments that 1) analytically validate a commercially available NP-1 sandwich immunoassay for use with human plasma and urine samples, 2) confirm the specificity of this assay, based on detection of NP-1 in plasma from wild-type but not oxytocin knockout mice, 3) demonstrate that NP-1 concentrations are markedly elevated in late pregnancy, consistent with studies showing substantial increases in plasma oxytocin throughout gestation, and 4) establish strong correlation between NP-1 and plasma oxytocin concentrations when oxytocin is measured in extracted (but not non-extracted) plasma. The NP-1 assay used in this study has strong analytical properties, does not require time-intensive extraction protocols, and the assay itself can be completed in
• Meyerson, B. E., Agley, J., Crosby, R. A., Bentele, K. G., Vadiei, N., Linde-Krieger, L. B., Russell, D. R., Fine, K., & Eldridge, L. A. (2024). ASAP: A pharmacy-level intervention to increase nonprescription syringe sales to reduce bloodborne illnesses. Research in social & administrative pharmacy : RSAP, 20(8), 778-785.
  More info

  Pharmacy syringe sales are effective structural interventions to reduce bloodborne illnesses in populations, and are legal in all but two states. Yet evidence indicates reduced syringe sales in recent years. This study was designed as a feasibility test of an intervention to promote syringe sales by pharmacies in Arizona.
• Allen, A. M., Valenti, M., Linde-Krieger, L. B., Medvescek, K., & Farland, L. V. (2023). Menstrual Phase Identification Questionnaire (MPIQ): Development and validation of a cross-sectional survey to identify follicular and luteal phases. Experimental and clinical psychopharmacology.
  More info

  Evidence continues to accumulate on the influence of the menstrual phase on several biobehavioral outcomes (e.g., substance misuse). Expansion of this knowledge is limited due to the burdensomeness of accurate menstrual phase assessment. Thus, we sought to create and validate a questionnaire that can be used as a stand-alone item within low-resource settings and numerous study designs (e.g., cross-sectional) to accurately identify both the follicular phase (FP) and the luteal phase (LP). Participants completed the self-administered four-item Menstrual Phase Identification Questionnaire (MPIQ) in two recently completed clinical trials. We assessed the accuracy of two MPIQ scoring criteria (less restrictive and more restrictive), as compared to self-report of onset of menses alone, with progesterone confirmation via dried blood spots. Participants ( = 59) were, on average, 33.7 (standard deviation []: ± 4.3) years old and provided a total of 83 responses. Assessing FP and LP using the self-reported onset of menses alone classified 65.1% of the responses with an overall phase identification accuracy of 60.2%. While the more restrictive MPIQ scoring classified 100% of the responses, it yielded a similar accuracy (68.4%). In contrast, the less restrictive MPIQ scoring classified 100% of the responses and also significantly improved phase identification accuracy to 92.1% ( < .001). The MPIQ, as a stand-alone item, allows all cross-sectional responses to be classified with a high level of accuracy. This low-burden questionnaire can be used alone to identify FP and LP in studies that may be otherwise limited by study design, finances, and/or participant burden. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
• Boullion, A., Linde-Krieger, L. B., Doan, S. N., & Yates, T. M. (2023). Parental warmth, adolescent emotion regulation, and adolescents' mental health during the COVID-19 pandemic. Frontiers in psychology, 14, 1216502.
  More info

  The United States (U.S.) Surgeon General Advisory has characterized the COVID-19 pandemic as a youth mental health crisis. Thus, elucidating factors affecting adolescents' mental health during the pandemic is important for supporting youth through current and future challenges. Parenting influences adolescents' ability to cope with stressors, and emotion regulation strategy use may underlie these effects.

Presentations

• Allen, A. M., Tecot, S. R., Rankin, L., & Krieger, L. B. (2024, July). Development of parental reflective functioning in mothers with and without opioid use disorder: Examining trajectories and correlates across the postpartum fourth trimester. International Attachment Conference. Routen, France.
• Boullion, A., Linde-Krieger, L. B., Sher-Censor, E., & Yates, T. M. (2024, May). Predictors of narrative features and correlates of adjustment among emancipated foster youth. . Association for Psychological Science Annual Convention. San Francisco, CA.
• Krieger, L. B., & Person-Rennell, N. (2024). A Life Course Approach to Understanding the Effects of Prenatal Substance Exposure: Teen and Young Adult Outcomes . 2024 Annual Santa Cruz County Dependency Conference. Nogales, AZ.
• Krieger, L. B., Meyerson, B. E., Huff, A. J., Carter, G. A., & Brady, B. R. (2023). Trauma Histories, Symptoms, and Vicarious Trauma among Opioid Treatment Program Staff: Implications for Provider Functioning and Treatment Delivery.. College on Problems of Drug Dependence 86th Annual Scientific meeting, June 15-19, 2024. Montreal Canada.: College on Problems of Drug Dependence.
• Linde-Krieger, L. B., & Allen, A. M. (2024, June). Loneliness During and After Pregnancy: Does it vary between those with and without opioid use disorder?. College on Problems of Drug Dependence 2024 Annual Meeting. Montreal, Canada.
• Linde-Krieger, L. B., & Allen, A. M. (2024, June). Loneliness and the mother-infant bond: Findings from mothers with Opioid Use Disorder and their infants during the transitional “fourth trimester.”. College on Problems of Drug Dependence 2024 Annual Meeting. Montreal, Canada.
• Allen, A. M., Linde-Krieger, L. B., Valenti, M., & Farland, L. (2023, April). Menstrual phase identification questionnaire (MPIQ): Development and validation of a cross-sectional survey. 44th Annual Meeting & Scientific Sessions of the Society of Behavioral Medicine. Phoenix, AZ.
• Linde-Krieger, L. B., Aringer, A., Rudd, K. L., & Yates, T. M. (2023, March). Youth post-traumatic stress during COVID-19: Evidence for high respiratory sinus arrhythmia as a susceptibility factor. Society for Research on Child Development Biennial Meeting. Salt Lake City, UT.

Poster Presentations

• Allen, A. M., Cusack, S., Linde-Krieger, L. B., & Nair, U. (2024, March). Relationship between physical activity and smoking outcomes in premenopausal women enrolled in a menstrual-phase timed smoking cessation trial.. 2024 Annual Meeting of the Society for Research on Nicotine and Tobacco. Edinburg, Scotland.
• Allen, A. M., Tecot, S. R., Linde-Krieger, L. B., Rankin, L., Valencia, E., Gonzolez, A., & Mallahan, S. (2024, June). Desires to Breastfeed and Impacts on Duration among Birthing People with and without Opioid Use Disorder.. College on Problems of Drug Dependence 2024 Annual Meeting. Montreal, Canada.
• Allen, A. M., Tecot, S. R., Rankin, L., Linde-Krieger, L. B., Rankin, L., Linde-Krieger, L. B., Tecot, S. R., & Allen, A. M. (2024, March). Postpartum nicotine/tobacco use: What is the association with bonding, connection, and oxytocin?. 2024 Annual Meeting of the Society for Research on Nicotine and Tobacco. Edinburg, Scotland.
• Brady, B. R., Carter, G. A., Huff, A. J., Meyerson, B. E., & Krieger, L. B. (2024, June 15-19). Trauma Histories, Symptoms, and Vicarious Trauma among Opioid Treatment Program Staff: Implications for Provider Functioning and Treatment Delivery. College on Problems of Drug Dependence 86th Annual Scientific meeting. Montreal, Canada: College on Problems of Drug Dependence.
• Brady, B. R., Huff, A. J., Carter, G. A., Krieger, L. B., & Meyerson, B. E. (2024). Making Connections to Improve Methadone Treatment: Are OTP Staff Work Characteristics, Lived SUD Experience and Trauma Associated with Beliefs about Trauma-Informed and Patient-Centered Care? . HEAL Scientific MeetingNational Institutes of Health.
• Chalke, A. M., Krieger, L. B., Tecot, S. R., & Allen, A. M. (2024, November). Association between breastfeeding and maternal sleep quality among mothers with opioid use disorder. Academy of Breastfeeding Medicine 29th Annual Conference. Schaumburg, IL: Academy of Breastfeeding Medicine.
• Nair, U., Linde-Krieger, L. B., Cusack, S., & Allen, A. M. (2024, March). Differences in cessation risk factors by menstrual timing versus no menstrual timing.. 2024 Annual Meeting of the Society for Research on Nicotine and Tobacco. Edinburg, Scotland.
• Brady, B. R., Carter, G. A., Krieger, L. B., Mahoney, A., Russell, D., & Meyerson, B. E. (2023, 17-20 October, 2023.). MPACT: Methadone patient access to collaborative treatment.. International Network for Health and Hepatitis in Substance Users (INHSU), 11th Annual International Conference. Geneva, Switzerland: International Network for Health and Hepatitis in Substance Users (INHSU).
• Linde-Krieger, L. B., Ryan, C., & Allen, A. M. (2023, March). Adverse experiences among mothers with opioid use disorder: Implications for caregiving behavior and mother-infant bonding. . Society for Research on Child Development Biennial Meeting. Salt Lake City, UT.
• Mallahan, S., Linde-Krieger, L. B., Rankin, L., Tecot, S. R., & Allen, A. M. (2023, June). Birth interventions among women with Opioid Use Disorder. . Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting.