Michael Frederick Morris

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Scholarly Contributions

Journals/Publications

• Janne d'Othée, B., Morris, M. F., Powell, R. J., & Bettmann, M. A. (2019). Cost determinants of percutaneous and surgical interventions for treatment of intermittent claudication from the perspective of the hospital. Cardiovascular and interventional radiology, 31(1), 56-65.
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  To identify pretreatment predictors of procedural costs in percutaneous and surgical interventions for intermittent claudication due to aortoiliac and/or femoropopliteal disease.
• Lazkani, M., Singh, N., Howe, C., Patel, N., Colón, M. J., Tasset, M., Amabile, O., Morris, M., Fang, H. K., & Pershad, A. (2019). An updated meta-analysis of TAVR in patients at intermediate risk for SAVR. Cardiovascular revascularization medicine : including molecular interventions, 20(1), 57-69.
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  Transcatheter aortic valve replacement (TAVR) has been approved for use in patients with severe aortic stenosis at intermediate, high and extreme surgical risk. This meta-analysis was performed to assess the safety and efficacy of TAVR compared to surgical aortic valve replacement (SAVR) in intermediate risk patients.
• Menon, N., Perez-Velez, C. M., Wheeler, J. A., Morris, M. F., Amabile, O. L., Tasset, M. R., & Raschke, R. A. (2019). Extracorporeal membrane oxygenation in acute respiratory distress syndrome due to influenza A (H1N1)pdm09 pneumonia. A single-center experience during the 2013-2014 season. Revista Brasileira de terapia intensiva, 29(3), 271-278.
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  This report aimed to describe the outcomes of the patients with severe H1N1 associated acute respiratory distress syndrome who were treated with extracorporeal membrane oxygenation therapy.
• Kobayashi, A., Lazkani, M., Moualla, S., Orazio, A., Tasset, M., Morris, M., Fang, K., & Pershad, A. (2018). Impact of aortic aneurysms in trans-catheter aortic valve replacement: A single center experience. Indian heart journal, 70 Suppl 3, S303-S308.
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  Patients who undergo trans-catheter aortic valve replacement (TAVR) may have concomitant aortic aneurysms. We sought to clarify the incidence of aortic aneurysms and its impact on clinical outcomes among patients undergoing TAVR.
• Morris, M. F., Lazkani, M., Stanich, M., Fang, H. K., & Pershad, A. (2018). Software Modeling to Predict Paravalvular Leak Following Transcatheter Mitral Valve Replacement. JACC. Cardiovascular interventions, 11(20), e167-e169.
• Morris, M. F., Verma, D. R., Sheikh, H., Su, W., & Pershad, A. (2018). Outcomes after magnetic resonance imaging in patients with pacemakers and defibrillators and abandoned leads. Cardiovascular revascularization medicine : including molecular interventions, 19(6), 685-688.
• Adusumalli, S., Morris, M., & Pershad, A. (2016). Pseudo-Pericardial Tamponade From Right Ventricular Hematoma After Chronic Total Occlusion Percutaneous Coronary Intervention of the Right Coronary Artery: Successfully Managed Percutaneously With Computerized Tomographic Guided Drainage. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 88(1), 86-8.
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  This is the first case reported in the literature of regional tamponade physiology following chronic total occlusion (CTO) percutaneous coronary intervention (PCI) of the right coronary artery (RCA) with compression of the right sided chambers that was managed percutaneously with computerized tomographic (CT) guided drainage. This case report highlights the heightened index of suspicion needed to make the diagnosis; the often nondiagnostic nature of the surface echocardiogram and the need for cross specialty collaboration to treat this entity successfully.
• Lazkani, M., Verma, D. R., Gellert, G., Morris, M., Fang, K., & Pershad, A. (2016). Limitations of Transcatheter Mitral Valve Replacement in Native Mitral Valve Disease With Severe Mitral Annular Calcification: Should it Be Performed Outside the Purview of a Clinical Trial?. JACC. Cardiovascular interventions, 9(23), 2460-2461.
• Lazkani, M., Verma, D. R., Morris, M., & Pershad, A. (2016). "Putting it all together": Highlighting the global approach to chronic total occlusion revascularization. Indian heart journal, 68 Suppl 2, S28-S31.
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  Preprocedural planning and advanced imaging is vital to achieve a consistent and high level of success for complex coronary chronic total occlusion (CTO) revascularization. Various practice patterns exist around the world when performing coronary artery CTO revascularization. This case report highlights a fusion of global practices in CTO intervention and integration of advanced imaging to achieve successful revascularization.
• Verma, D. R., Pershad, Y., Pershad, A., Fang, K., Gellert, G., & Morris, M. F. (2016). Impact of institutional volume and experience with CT interpretation on sizing of transcatheter aortic valves: A multicenter retrospective study. Cardiovascular revascularization medicine : including molecular interventions, 17(8), 566-570.
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  Computed tomography (CT) has become the standard imaging modality for pre-procedural aortic annular sizing prior to transcatheter aortic valve replacement (TAVR). We hypothesized that the accuracy of CT derived annular measurements would be greater at sites with higher TAVR procedural volume.
• Mayer, A. P., Morris, M. F., Panse, P. M., Ko, M. G., Files, J. A., Ruddy, B. E., & Blair, J. E. (2013). Does the presence of mediastinal adenopathy confer a risk for disseminated infection in immunocompetent persons with pulmonary coccidioidomycosis?. Mycoses, 56(2), 145-9.
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  Pulmonary coccidioidomycosis is caused by inhaling airborne arthroconidia of Coccidioides, a soil-dwelling fungus endemic to the desert southwestern United States. Although uncommon, disseminated coccidioidal infection can be associated with well-defined risk factors, such as cell-mediated immunodeficiency, certain racial heritages (e.g. African or Filipino), male sex, or pregnancy. Before widespread use of computed tomography (CT), the presence or persistence of mediastinal lymphadenopathy was postulated to be a risk factor for disseminated coccidioidal infection. To investigate the use of CT scanning to identify the presence of mediastinal lymphadenopathy in patients with pulmonary coccidioidomycosis, and to correlate such lymphadenopathy with disseminated coccidioidal infection, we performed a retrospective review of patients with pulmonary coccidioidomycosis who were evaluated by chest CT. Two radiologists independently interpreted 150 CT scans from patients with pulmonary coccidioidomycosis. Forty-nine patients met CT criteria for mediastinal lymphadenopathy, whereas 101 patients did not. Disseminated coccidioidal infection was observed in 5 (10%) of the 49 patients with mediastinal lymphadenopathy and in 6 of the 101 (6%; P = .34) without such adenopathy. Among patients with coccidioidomycosis, patients with mediastinal lymphadenopathy, as assessed by CT, had a higher rate of disseminated infection, but the difference was not statistically significant.
• Morris, M. F., Suri, R. M., Akhtar, N. J., Young, P. M., Gruden, J. F., Burkhart, H. M., & Williamson, E. E. (2013). Computed tomography as an alternative to catheter angiography prior to robotic mitral valve repair. The Annals of thoracic surgery, 95(4), 1354-9.
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  Computed tomography angiography (CTA) of the coronary arteries has been proposed as an alternative screening modality to catheter coronary angiography (CCA) prior to noncoronary cardiac surgery. The safety and utility of preoperative coronary CTA in patients undergoing robotic mitral valve repair is unknown.
• Pershad, A., Stone, D., Morris, M. F., Fang, K., & Gellert, G. (2013). Aortic annulus measurement and relevance to successful transcatheter aortic valve replacement: a new technique using 3D TEE. Journal of interventional cardiology, 26(3), 302-9.
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  There are limitations of using 2D imaging to accurately size the aortic annulus. This article highlights the limitations of 2D technology and proposes a new 3D TEE method for sizing of the aortic annulus.
• Morris, M. F., Adams, J. C., Panse, P. M., & Srivathsan, K. (2012). Radiofrequency ablation complicated by left atrial intramural hematoma. Journal of cardiovascular electrophysiology, 23(6), 662-3.
• Morris, M. F., Gardner, B. A., Gotway, M. B., Thomsen, K. M., Harmsen, W. S., & Araoz, P. A. (2012). CT findings and long-term mortality after pulmonary embolism. AJR. American journal of roentgenology, 198(6), 1346-52.
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  The utility of CT findings in predicting long-term mortality in patients with acute pulmonary embolism (PE) is unknown. The purpose of this study is to retrospectively determine whether three CT findings--increased embolic burden, interventricular septal bowing toward the left ventricle, and right ventricle-to-left ventricle (RV/LV) diameter ratio greater than 1--are independent predictors of long-term all-cause mortality after acute PE.
• Morris, M. F., Staley, L. L., Arabia, F. A., DeValeria, P. A., & Collins, J. M. (2012). Abdominal X-ray imaging for detection of left ventricular assist device driveline damage. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31(12), 1313-5.
• Young, P. M., Glockner, J. F., Williamson, E. E., Morris, M. F., Araoz, P. A., Julsrud, P. R., Schaff, H. V., Edwards, W. D., Oh, J. K., & Breen, J. F. (2012). MR imaging findings in 76 consecutive surgically proven cases of pericardial disease with CT and pathologic correlation. The international journal of cardiovascular imaging, 28(5), 1099-109.
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  To describe findings of patients with surgically confirmed pericardial disease on state of the art MR sequences. Retrospective review was performed for patients who underwent pericardiectomy and preoperative MR over a 5 year period ending in 2009. Patients' records were reviewed to confirm the diagnosis of chronic recurrent pericarditis, constrictive pericarditis, or pericardial tumor. MR imaging findings of pericardial thickness, IVC diameter, presence or absence of pericardial or pleural effusion, pericardial edema, pericardial enhancement, and septal "bounce" were recorded. Patients with constriction had a larger IVC diameter (3.1 ± 0.4 cm) than patients with recurrent pain and no constriction (2.0 ± 0.4 cm). Mean pericardial thickness for the 16 patients with chronic recurrent pericarditis but no evidence of constriction was 4.8 ± 2.9 mm. Mean pericardial thickness for patients with constriction was 9.2 ± 7.0 cm with calcification, and 4.6 ± 2.1 cm without calcification. 94% of patients with chronic recurrent pericarditis had gadolinium enhancement of the pericardium, while 76% of patients with constriction had pericardial enhancement. Septal "bounce" was present in 19% of chronic recurrent pericarditis cases and 86% of constriction cases. 5 patients had a pericardial neoplasm, 1 of which was not identified preoperatively. State of the art MR techniques can identify significant and distinct findings in patients with chronic recurrent pericarditis, constrictive pericarditis, and pericardial tumors.
• Bonnichsen, C. R., Sundt, T. M., Anavekar, N. S., Foley, T. A., Morris, M. F., Martinez, M. W., Williamson, E. E., Glockner, J. F., & Araoz, P. A. (2011). Aneurysms of the ascending aorta and arch: the role of imaging in diagnosis and surgical management. Expert review of cardiovascular therapy, 9(1), 45-61.
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  Thoracic aortic aneurysms tend to be asymptomatic and were previously often diagnosed only after a complication such as dissection or rupture occurred. Better imaging techniques and an increase in the use of cross-sectional imaging has led to an increase in the diagnosis of aortic aneurysms, which has allowed for elective treatment prior to the development of a complication. The location, size and etiology of an aneurysm all impact the clinical outcomes and these factors are used to determine the appropriate timing of surgical replacement. Surgeons often rely on the information obtained from preoperative imaging to determine when to intervene and what type of procedure will be necessary, making it important for the radiologist to understand these issues in order to provide the necessary information. Postoperative imaging after surgical replacement of the aorta is also important, as there are some common findings that occur in this patient population that can impact how they are treated. The purpose of this article is to review the etiology and associated findings of aneurysms of the ascending aorta and arch, with a focus on how computed tomography angiography and magnetic resonance angiography findings are used to determine the appropriate timing for elective replacement and the type of surgical procedure, as well as the role of follow-up imaging. This will include a review of the most commonly performed types of surgical procedures, to provide an understanding of how the findings of preoperative imaging studies impact what the surgeon does in the operating room, as well as the expected findings of postoperative imaging studies.
• Morris, M. F., Williamson, E. E., Topilsky, Y., Espinosa, R. E., Cetta, F., Burkhart, H. M., Enriquez-Sarano, M., Suri, R. M., & Michelena, H. I. (2011). Multi-imaging assessment of the congenital mitral arcade. Journal of the American College of Cardiology, 57(18), 1856.
• Anavekar, N. S., Bonnichsen, C. R., Foley, T. A., Morris, M. F., Martinez, M. W., Williamson, E. E., Glockner, J. F., Miller, D. V., Breen, J. F., & Araoz, P. A. (2010). Computed tomography of cardiac pseudotumors and neoplasms. Radiologic clinics of North America, 48(4), 799-816.
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  Important features of cardiac masses can be clearly delineated on cardiac computed tomography (CT) imaging. This modality is useful in identifying the presence of a mass, its relationship with cardiac and extracardiac structures, and the features that distinguish one type of mass from another. A multimodality approach to the evaluation of cardiac tumors is advocated, with the use of echocardiography, CT imaging and magnetic resonance imaging as appropriately indicated. In this article, various cardiac masses are described, including pseudotumors and true cardiac neoplasms, and the CT imaging findings that may be useful in distinguishing these rare entities are presented.
• Morris, M. F., Maleszewski, J. J., Suri, R. M., Burkhart, H. M., Foley, T. A., Bonnichsen, C. R., Anavekar, N. S., Young, P. M., Williamson, E. E., Glockner, J. F., & Araoz, P. A. (2010). CT and MR imaging of the mitral valve: radiologic-pathologic correlation. Radiographics : a review publication of the Radiological Society of North America, Inc, 30(6), 1603-20.
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  Computed tomography (CT) and magnetic resonance (MR) imaging are increasingly important adjuncts to echocardiography for the evaluation of mitral valve disease. The mitral valve may be involved in various acquired or congenital conditions with resultant regurgitation or stenosis, and many of these conditions can be identified with CT or MR imaging. In addition, CT is useful for detecting and monitoring postoperative complications after mitral valve repair or replacement. As the use of CT and MR imaging increases, awareness of the CT and MR imaging appearances of the normal mitral valve and the various disease processes that affect it may foster recognition of unsuspected mitral disease in patients undergoing imaging for other purposes. Supplemental material available at http://radiographics.rsna.org/lookup/suppl/doi:10.1148/rg.306105518/-/DC1.
• Morris, M. F., Zhang, Y., Zhang, H., Prowda, J. C., Silvers, D. N., Fawwaz, R. A., & Prince, M. R. (2009). Features of nephrogenic systemic fibrosis on radiology examinations. AJR. American journal of roentgenology, 193(1), 61-9.
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  The objective of this article is to illustrate the spectrum of imaging findings with photographic and histopathologic correlation in patients with biopsy-proven nephrogenic systemic fibrosis (NSF).

Presentations

• Morris, M., Hu, C., Verma, D., Schwemmer, C., Schmiedeskamp, H., & Pershad, A. (2019, Fall). Diagnostic Performance of a Machine Learning FFRct Prototype Across Multiple CT Vendors. Radiological Society of North America's 106th Scientific Assembly and Annual Meeting. November 27 - December 2, 2020, Chicago, IL.