Christian O Twiss
- Associate Professor, Surgery - (Clinical Scholar Track)
- M.D. Medicine
- New York University School of Medicine, New York, New York, United States
- B.A. Biology
- Brown University, Providence, Rhode Island, United States
- "Angiotensin II and Cardiomyocyte Hypertrophy in vitro"
- Associate Residency Program Director, University of Arizona, Tucson, Arizona (2014 - Ongoing)
- Associate Professor of Surgery, University of Arizona, Tucson, Arizona (2013 - Ongoing)
- Assistant Professor of Surgery, University of Arizona, Tucson, Arizona (2008 - 2013)
- Best Surgical Video Award
- Society of Urodynamics, Female Pelvic Medicine, and Urogenital Reconstruction (SUFU), Winter 2017
- Vice Chair Judicial & Ethics Committee
- American Urological Association, Spring 2017 (Award Nominee)
- Faculty Teaching Award
- University of Arizona, Spring 2012
- Best Science Presentation Award
- International Continence Society, Spring 2007
- Best of Posters Award
- AUA, Spring 2006
- Research Grant Awardee
- American Urogynecologic Society Foundation, Spring 2006
Licensure & Certification
- Diplomate, American Board of Urology, Subspecialty Certification in FPMRS (2013)
- California Medical License, California Medical Board (2006)
- Arizona Medical License, Arizona Medical Board (2008)
- Diplomate, American Board of Urology (2010)
No activities entered.
UrologySURG 815E (Fall 2013)
Urology (Surgery Subspecialty)SURG 807H (Fall 2013)
- Twiss, C. O., & Rosenblum, N. (2008). Perineal Hernia and Perineocele. In Female Urology, 3rd Ed.. Saunders Press.
- Twiss, C. O., Triaca, V., Konijeti, R., & Raz, S. (2008). Surgery for Pelvic Floor Relaxation. In Textbook of Reconstructive Urologic Surgery. Informa Press.
- Michalak, J., Lin, F., & Twiss, C. O. (2017). Preoperative Evaluation and Optimization of the Geriatric Urologic Patient. Urology Practice, 4, 499-507. doi:http://dx.doi.org/10.1016/j.urpr.2016.10.006
- Dyer, A. J., & Twiss, C. O. (2014). Painful bladder syndrome: an update and review of current management strategies. Current urology reports, 15(2), 384.More infoInterstitial cystitis/painful bladder syndrome (IC/PBS) remains a prevalent, but untreated disease with a poorly understood pathophysiology. Nonetheless, four main processes currently appear to be involved in producing IC/PBS symptoms: (1) disruption of the bladder GAG/proteoglycan layer, (2) upregulated immune/inflammatory response, (3) neural upregulation, and (4) pelvic floor dysfunction. Current and emerging therapies aimed at these potential targets will be the focus of this review with an update on IC/PBS therapy.
- Onyishi, S. E., & Twiss, C. O. (2014). Pressure flow studies in men and women. The Urologic clinics of North America, 41(3), 453-67, ix.More infoThere are well established pressure flow criteria and nomograms for urinary obstruction in men. The pressure flow criteria for female urinary obstruction are not well established due to differences in female voiding dynamics as compared to men. Typically, other information such as radiographic data and clinical symptoms are needed to facilitate the diagnosis. Detrusor underactivity remains a poorly studied clinical condition without definitive urodynamic diagnostic criteria. Modalities proposed for objective analysis of detrusor function such as power (watt) factor, linear passive urethral resistance relation and BCI nomogram were all developed to analyze male voiding dysfunction. Overall, further investigation is needed to establish acceptable urodynamic criteria for defining detrusor underactivity in women.
- Twiss, C. O., Brown, C., & Sylvester, O. (2014). Detrusor Underactivity and Detrusor Hyperactivity with Impaired Contractility. Current Bladder Dysfunction Reports, 9, 341-349.
- Nelson, P. S., Lee, P., Terris, M. K., Culig, Z., Wang, Z., & Twiss, C. O. (2013). American Journal of Clinical and Experimental Urology: Editorial Board (2013) e-Century Publishing Corporation. American journal of clinical and experimental urology, 1(1), 83-4.
- Terris, M. K., Wang, Z., Culig, Z., Twiss, C. O., Lee, P., & Nelson, P. S. (2013). Launching of american journal of clinical and experimental urology. American journal of clinical and experimental urology, 1(1), 1-2.
- Twiss, C. O., Kilpatrick, L., Craske, M., Buffington, T., Ornitz, E., Rodriguez, L., Mayer, E. A., & Naliboff, B. D. (2009). Increased Startle Responses in Interstitial Cystitis: Evidence for Central Hyperresponsiveness to Visceral-Related Threat. Journal of Urology, 181, 2127-33.
- Twiss, C. O., & Raz, S. (2008). Complications of Synthetic Mid-Urethral Slings. Issues in Incontinence.
- Twiss, C. O., Triaca, V., Bergman, J., & Rodriguez, L. V. (2008). The Epidemiology, Social Burden and Genetics of Pelvic Organ Prolapse. Current Bladder Dysfunction, 3, 90-94.
- Velez-Carrasco, W., Merkel, M., Twiss, C. O., & Smith, J. D. (2008). Dietary methionine effects on plasma homocysteine and HDL metabolism in mice. The Journal of nutritional biochemistry, 19(6), 362-70.More infoThe effects of dietary manipulation of folate and methionine on plasma homocysteine (Hcy) and high-density lipoprotein cholesterol (HDL-C) levels in wild-type and apolipoprotein-E-deficient mice were determined. A low-folate diet with or without folate and/or methionine supplementation in drinking water was administered for 7 weeks. Fasted Hcy rose to 23 microM on a low-folate/high-methionine diet, but high folate ameliorated the effect of high methionine on fasted plasma Hcy to approximately 10 microM. Determination of nonfasted plasma Hcy levels at 6-h intervals revealed a large diurnal variation in Hcy consistent with a nocturnal lifestyle. The daily average of nonfasted Hcy levels was higher than fasted values for high-methionine diets but lower than fasted values for low-methionine diets. An acute methionine load by gavage of fasted mice increased plasma Hcy 2.5 h later, but mice that had been on high-methionine diets had a lower fold induction. Mice fed high-methionine diets weighed less than mice fed low-methionine diets. Based on these results, two solid-food diets were developed: one containing 2% added methionine and the other containing 2% added glycine. The methionine diet led to fasted plasma Hcy levels of >60 microM, higher than those with methionine supplementation in drinking water. Mice on methionine diets had >20% decreased body weights and decreased HDL-C levels. An HDL turnover study demonstrated that the HDL-C production rate was significantly reduced in mice fed the methionine diet.
- Triaca, V., Twiss, C. O., & Raz, S. (2007). Urethral compression for the treatment of postprostatectomy urinary incontinence: is history repeating itself?. European urology, 51(2), 304-5.
- Twiss, C. O., Fischer, M. C., & Nitti, V. W. (2007). Comparison between reduction in 24-hour pad weight, International Consultation on Incontinence-Short Form (ICIQ-SF) score, International Prostate Symptom Score (IPSS), and Post-Operative Patient Global Impression of Improvement (PGI-I) score in patient evaluation after male perineal sling. Neurourology and urodynamics, 26(1), 8-13.More infoWe assessed the utility of three self-assessment instruments: the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), the post-operative Patient Global Impression of Improvement (PGI-I) score, and the International Prostate Symptom Score (IPSS) by correlating them with an objective outcome, the change in 24-hr pad weight, after a male perineal sling.
- Twiss, C. O., Triaca, V., & Raz, S. (2007). The Posterior Compartment: Evaluation and Functional Outcomes after Surgical Repair. Current Bladder Dysfunction Report, 2, 205-13.
- Twiss, C. O., Triaca, V., & Rodriguez, L. V. (2007). Familial Transmission of Urogenital Prolapse and Incontinence. Current Opinion Ob Gyn, 19, 464.
- Twiss, C. O., Fleischmann, N., & Nitti, V. (2005). Correlation of Abdominal Leak Point Pressure with Objective Incontinence Severity in Men with Post-Prostatectomy Stress Incontinence. Neurourology and Urodynamics, 24, 207.
- Twiss, C. O., Huackabay, C., Berger, A., & Nitti, V. W. (2005). A Urodynamics Protocol to Optimally Assess Men with Post-Prostatectomy Incontinence. Neurourology and Urodynamics, 24, 622.
- Arif Tiwari, H., Costello, J. R., Funk, J., Kalb, B. T., Martin, D. R., Meshksar, A., Petkovska, I., Czeyda-Pommersheim, F., & Twiss, C. O. (2016, April). Comparative Evaluation of Defecography Phase to Non-Defecography Valsalva Maneuver in Dynamic Pelvic Floor MRI. Canadian Association of Radiologists, 79th Annual Scientific Meeting (ASM). Montreal, QC.
- Twiss, C. O., Arif, H. M., Kalb, B., Funk, J. T., & Martin, D. (2014, Spring). Addition of a Defecography Phase to Dynamic Pelvic MRI Enhances Detection and Visualization of Pelvic Organ Prolapse. American Urological Association Meeting. Orlando, FL: AUA.
- Bergerson, A., Austin, E., Bricklin, L., Price, E., Funk, J., & Twiss, C. O. (2017, Summer). Impact of Transvaginal Mesh Removal on Vaginal Pain, Urinary Incontinence, and Pelvic Organ Prolapse. Western Section American Urological Association Meeting. Vancouver, BC.
- Lin, F., Craig, M., Twiss, C. O., & Funk, J. (2017, March). Total autologous fascia lata anterior repair and vaginal vault suspension: A new technique!. Society of Urodynamics, Female Pelvic Medicine & Urogential Reconstruction.More infoVideo presentation