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Jonathan R Walker

  • Associate Professor, Urology - (Clinical Scholar Track)
Contact
  • (520) 626-6236
  • Arizona Health Sciences Center, Rm. 5408
  • Tucson, AZ 85724
  • walkerj1@arizona.edu
  • Bio
  • Interests
  • Courses
  • Scholarly Contributions

Degrees

  • M.D.
    • Georgetown University College of Medicine, Washington, D.C. (District of Columbia), United States
  • B.S.
    • Rensselaer Polytechic Intitute School of Science, Troy, New York, United States
    • Cum Laude Graduate

Work Experience

  • University of Arizona, Tucson, Arizona (2014 - Ongoing)
  • University of Arizona, Tucson, Arizona (2007 - Ongoing)
  • Southern Arizona VA Healthcare Systems (2003 - Ongoing)
  • University of Arizona, Tucson, Arizona (2003 - Ongoing)
  • University Physicians Health Care (2003 - 2015)

Awards

  • Faculty Teaching Award by Urology Residents
    • Spring 2009
    • Spring 2007
  • LRP Grant Award Recipient
    • NIH/NCI, Spring 2000

Licensure & Certification

  • Arizona Medical License, Arizona Medical Board (2003)
  • Diplomate, American Board of Urology (2014)
  • Diplomate, American Board of Urology (2006)

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Interests

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Courses

2016-17 Courses

  • Urology (Surgery Subspecialty)
    SURG 837H (Spring 2017)

Related Links

UA Course Catalog

Scholarly Contributions

Journals/Publications

  • Arnold, S. J., Lin, F. C., Eldersveld, J. M., Phung, M. C., Walker, J. R., & Nguyen, T. T. (2016). Seminal Vesicle Leiomyoma Mimicking Extra-prostatic Extension of Prostatic Adenocarcinoma. Urology case reports, 6, 18-20.
    More info
    Leiomyomas are common smooth muscle neoplasms; however, leiomyomas of the seminal vesicles are extremely rare. We report a case of seminal vesicle leiomyoma in a 55-year-old African American male who underwent robot assisted laparoscopic prostatectomy (RALP) for Gleason 8 (4 + 4) adenocarcinoma. An incidental nodule arising from the left seminal vesicle was discovered during surgery, complicating the surgical dissection and suggesting extra-prostatic extension. The histologic findings in this case raised the possibility that this seminal vesicle leiomyoma may have arisen from a remnant of the mid-portion of the Müllerian duct; however, a thorough immunohistochemical (IHC) workup disproved this theory.
  • Bell, R. C., Austin, E. T., Arnold, S. J., Lin, F. C., Walker, J. R., & Larsen, B. T. (2016). Rare Leiomyoma of the Tunica Dartos: A Case Report with Clinical Relevance for Malignant Transformation and HLRCC. Case reports in pathology, 2016, 6471520.
    More info
    Background. Genital leiomyomas fall under the broader category of cutaneous leiomyomas, which are rare smooth muscle neoplasms accounting for 5% of all leiomyomas. Genital leiomyomas arising from the dartos muscle are exceedingly rare with fewer than 30 cases reported in the literature. They are typically benign and adequately treated with simple surgical excision; however, previously reported cases of malignant transformation and a possible link to the hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome warrant closer follow-up. Case Presentation. We report a case of a 47-year-old male refugee from Rwanda found to have a mobile, pea-sized, mildly painful scrotal lesion near the left penoscrotal junction and 1.5 cm indeterminate vascular mass in the right kidney. Surgical excision of the scrotal nodule was performed and the diagnosis of a dartoic leiomyoma was rendered. The presence of moderate nuclear atypia, rare mitotic activity, and close surgical margins prompted a wide reexcision. We report the surgical approach, pathologic findings, and clinical follow-up related to this scrotal lesion. Conclusion. Scrotal leiomyomas demonstrate a high rate of recurrence and pose a risk for malignant transformation. They may also indicate an underlying autosomal dominant syndrome associated with increased risk for development of an aggressive form of renal cell carcinoma. When discovered, management should include surgical excision, screening for syndromic features, and routine follow-up.
  • Satyanarayan, A., Redd, L., Dyer, A., Wright, A., & Walker, J. (2015). Adenocarcinoma of the urethra with mucinous features. Reviews in urology, 17(1), 38-41.
    More info
    Primary adenocarcinoma of the female urethra is a rare malignancy. Previous studies hypothesize multiple origins, including periurethral glands or intestinal metaplasia. We report a case of a 60-year-old white woman with adenocarcinoma of the urethra who initially presented with obstructive voiding complaints secondary to a urethral mass. Wide local excision revealed invasive adenocarcinoma of the urethra with mucinous features. There was intestinal metaplasia adjacent to the tumor, as well as separate identification of intestinal metaplasia along the urethra. Ultimately, the patient underwent radical cystectomy with ileal conduit urinary diversion with no evidence of recurrence, indicating the role of early identification and surgical intervention for such cases.

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